Evidence map›Paper›PMID 37698677›Full record

ArticleJournal of cancer research and clinical oncology2023

Naples score: a novel prognostic biomarker for breast cancer patients undergoing neoadjuvant chemotherapy.

Yuting Xiu, Cong Jiang, Qinghua Huang, Xiao Yu, Kun Qiao, Danping Wu, Xiaotian Yang, Shiyuan Zhang, Xiangshi Lu, Yuanxi Huang

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yuting Xiu *Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Cong Jiang *Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Qinghua Huang *Department of Breast Surgery, Wuzhou Red Cross Hospital, Wuzhou, 543000, China.
Xiao YuDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Kun QiaoDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Danping WuDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Xiaotian YangDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Shiyuan ZhangDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China.
Xiangshi LuDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China. luxiangshi@163.com.
Yuanxi HuangDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, 150086, China. rxwk@163.com.
Harbin Medical University · CNThird Affiliated Hospital of Harbin Medical University · CNWuzhou Red Cross Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe Naples Score (NPS) is a novel prognostic indicator that has been used in various cancers, but its potential in breast malignant tumor patients receiving neoadjuvant chemotherapy (NAC) has not been discovered. This study aimed to investigate the relationship between NPS and overall survival (OS) and disease-free survival (DFS) in breast cancer patients.

methodsA total of 217 breast cancer patients undergoing NAC were incorporated into this retrospectively research. K-M survival curves and log-rank tests are used to determine OS and DFS. Cox regression model was used to evaluate the relationship between NPS and OS and DFS. Nomogram was developed based on the results of multivariate Cox regression analysis. Prognostic models were internally validated using bootstrapping and the consistency index (C-index).

resultsAge group was correlated with NPS (p < 0.05). Low and moderate Naples risk patients had higher 5-year OS and DFS rates than high risk Naples patients (93.8% vs. 75.4% vs. 60.0%; X

conclusionsIn breast cancer patients who have undergone NAC, NPS is a novel prognostic indicator. NPS combined with clinicopathological features showed good predictive ability, and its performance was better than that of traditional pathological TNM staging.

Indexed as

Breast NeoplasmsBiomarkersFemaleHumansNeoadjuvant TherapyPrognosisRetrospective StudiesBiomarkersBreast cancerNaples scoreNeoadjuvant chemotherapyNomogram

Identifiers

PMID37698677
PMCPMC11797591
OpenAlexW4386623977

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.