Evidence map›Paper›PMID 37698808›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2023

Pharmacotherapy for Traumatic Brain Injury: The Next Generation of Clinical Trials.

Ramon Diaz-Arrastia, Patrick M Kochanek

Open access · greenAbstract readEditorial
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Neuroprotective therapy after traumatic brain injury: does the window for treatment extend for months?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ramon Diaz-ArrastiaTraumatic Brain Injury Clinical Research Center, Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA. Ramon.Diaz-Arrastia@pennmedicine.upenn.edu.
Patrick M KochanekDepartment of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA. kochanekpm@pitt.edu.
University of Pennsylvania · USUniversity of Pittsburgh · US

Funding

Brain Oxygen Optimization in Severe Traumatic Brain Injury - Phase 3 (BOOST-3)U01NS099046 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ramon Diaz-Arrastia, Lori Shutter · 2018 to 2026
$35.7M
Clinical Validation of Serum Neurofilament Light as a Biomarker of Traumatic Axonal InjuryU01NS114140 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DIAZ-ARRASTIA, RAMON · 2020 to 2025
$3.9M
A Translational Evaluation of Sur1-Trpm4 Imaging Endophenotypes and Genetics to Direct Precision Medicine for Cerebral Edema After Traumatic Brain InjuryR01NS115815 · NINDS · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI JHA, RUCHIRA MENKA · 2021 to 2025
$2.8M
NINDS NIH HHS R01 NS115815NINDS NIH HHS U01 NS099046NINDS NIH HHS U01 NS114140
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain Injuries, TraumaticHumans

Identifiers

PMID37698808
PMCPMC10684833
OpenAlexW4386624662

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.