Evidence map›Paper›PMID 37700775›Full record

ArticleClinical case reports2023

Persistently high serum aspartate aminotransferase level in an asymptomatic young patient.

Xiong Pei, Yanhua Zhao, Wei Jiang, Qingmin Zeng, Changhai Liu, Ming Wang, Hui Wang, Shanshan Liang, Wei Gan, Dongbo Wu and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Xiong PeiCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Yanhua ZhaoDepartment of Laboratory Medicine West China Hospital, Sichuan University Chengdu China.
Wei JiangCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Qingmin ZengCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Changhai LiuCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Ming WangCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Hui WangDepartment of Laboratory Medicine West China Hospital, Sichuan University Chengdu China.
Shanshan LiangDepartment of Laboratory Medicine West China Hospital, Sichuan University Chengdu China.
Wei GanDepartment of Laboratory Medicine West China Hospital, Sichuan University Chengdu China.
Dongbo WuCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.ORCID https://orcid.org/0000-0003-4500-047X
Hong TangCenter of Infectious Diseases West China Hospital, Sichuan University Chengdu China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: We report a young man with isolated elevated AST. He had no other evidence of liver or other related diseases. All the tests and examination reports were negative. The final diagnosis of macro-AST was confirmed by PEG precipitation tests. Abstract: Elevated liver enzymes, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), may commonly indicate liver injury. However, macro-AST is generally a benign condition that may be considered as pathologic by clinicians. A young man with isolated elevated AST for more than 10 years who have taken extensive tests and examinations was diagnosed with macro-AST in our article. Thus, in patients with isolated AST-elevation, polyethylene glycol (PEG) precipitation test was recommended to test whether macro-AST could be diagnosed.

Indexed as

aspartate aminotransferasemacro‐ASTmacroenzymepolyethylene glycol

Identifiers

PMID37700775
PMCPMC10493240
OpenAlexW4386606414

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.