Evidence map›Paper›PMID 37701438›Full record

ArticleFrontiers in immunology2023

Platelet status in cancer cachexia progression in Apc

Patrice Cunningham, Christian A Unger, Emma A Patton, Akyla Aiken, Alea Browne, Ella James, Ahmed K Aladhami, Marion C Hope Rd, Brandon N VanderVeen, Thomas D Cardaci and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Transforming Growth Factors in Venous Thrombus Formation and Resolution.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Patrice CunninghamDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Christian A UngerDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Emma A PattonDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Akyla AikenDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Alea BrowneDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Ella JamesDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Ahmed K AladhamiDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Marion C Hope RdDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Brandon N VanderVeenDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Thomas D CardaciDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
E Angela MurphyDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Reilly T EnosDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
Kandy T VelázquezDepartment of Pathology, Microbiology, and Immunology, School of Medicine, University of South Carolina, Columbia, SC, United States.
University of South Carolina · USColumbia VA Health Care System · US

Funding

U-RISE at Claflin University through Collaborative Interdisciplinary Mentoring in Biomedical SciencesT34GM136495 · NIGMS · CLAFLIN UNIVERSITY · PI ASSANIE-SHIVJI, SAMINA NOORALI, MCCUTCHEON, GLORIA S · 2021 to 2024
$1.7M
NIGMS NIH HHS T34 GM136495
6 · The paper itself

Abstract

Cachexia, a complex wasting syndrome, significantly affects the quality of life and treatment options for cancer patients. Studies have reported a strong correlation between high platelet count and decreased survival in cachectic individuals. Therefore, this study aimed to investigate the immunopathogenesis of cancer cachexia using the Apc

Indexed as

Blood PlateletsColonic NeoplasmsAnimalsCachexiaDisease Models, AnimalMiceQuality of Lifemuscle wastingphysical activityplateletsred blood cellsTGFβ

Identifiers

PMID37701438
PMCPMC10493779
OpenAlexW4386224768

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.