Evidence map›Paper›PMID 37702461›Full record

ArticleGut microbes2023

Distinctive patterns of sulfide- and butyrate-metabolizing bacteria after bariatric surgery: potential implications for colorectal cancer risk.

Hisham Hussan, Steven K Clinton, Elizabeth M Grainger, Maxine Webb, Cankun Wang, Amy Webb, Bradley Needleman, Sabrena Noria, Jiangjiang Zhu, Fouad Choueiry and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Hisham HussanDivision of Gastroenterology, Department of Internal Medicine, University of California, Davis; Sacramento, CA, USA.ORCID 0000-0002-8646-8370
Steven K ClintonDivision of Medical Oncology; Department of Internal Medicine, The Ohio StateUniversity, Columbus, OH, USA.
Elizabeth M GraingerDivision of Medical Oncology; Department of Internal Medicine, The Ohio StateUniversity, Columbus, OH, USA.
Maxine WebbDivision of Medical Oncology; Department of Internal Medicine, The Ohio StateUniversity, Columbus, OH, USA.
Cankun WangDivision of Biomedical Informatics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Amy WebbDivision of Biomedical Informatics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Bradley NeedlemanCenter for Minimally Invasive Surgery; Department of General Surgery, The Ohio State University, Columbus, OH, USA.
Sabrena NoriaCenter for Minimally Invasive Surgery; Department of General Surgery, The Ohio State University, Columbus, OH, USA.
Jiangjiang ZhuThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Fouad ChoueiryThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Maciej PietrzakDivision of Biomedical Informatics, Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Michael T BaileyThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
The Ohio State University · USCenter for Special Minimally Invasive and Robotic Surgery · USCalifornia State University, Sacramento · USNationwide Children's Hospital · US

Funding

Characterizing the Metabolome and Volatilome of Gut MicrobiomeR35GM133510 · NIGMS · OHIO STATE UNIVERSITY · PI ZHU, JIANGJIANG · 2019 to 2023
$2.2M
NIGMS NIH HHS R35 GM133510
6 · The paper itself

Abstract

Despite improved cardiometabolic outcomes following bariatric surgery, its long-term impact on colorectal cancer (CRC) risk remains uncertain. In parallel, the influence of bariatric surgery on the host microbiome and relationships with disease outcomes is beginning to be appreciated. Therefore, we investigated the impact of Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG) on the patterns of sulfide-reducing and butyrate-producing bacteria, which are hypothesized to modulate CRC risk after bariatric surgery. In this single-center, cross-sectional study, we included 15 pre-surgery subjects with severe obesity and patients who are at a median (range) of 25.6 (9.9-46.5) months after RYGB (

Indexed as

Bariatric SurgeryColorectal NeoplasmsGastrointestinal MicrobiomeAgedBacteriaButyratesCross-Sectional StudiesEscherichia coliFemaleHumansMaleMiddle AgedButyratesBariatricbutyratecolorectal cancermicrobiomesulfide-reducing

Identifiers

PMID37702461
PMCPMC10501170
OpenAlexW4386705271

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.