Evidence map›Paper›PMID 37718901›Full record

ArticleJournal of bone metabolism2023

Dental Pulp Stem Cells and Current in vivo Approaches to Study Dental Pulp Stem Cells in Pulp Injury and Regeneration.

Dongwook Yang, Jea Giezl Niedo Solidum, Dongsu Park

Open access · hybridAbstract read
In one paragraph

Article in Journal of bone metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Dongwook YangDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Jea Giezl Niedo SolidumDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Dongsu ParkDepartment of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · US

Funding

Hematology Training ProgramT32DK060445 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI GOODELL, MARGARET A. · 2002 to 2023
$8.3M
Regulation of Skeletal progenitor cells in Osteogenesis ImperfectaR01DE031288 · NIDCR · BAYLOR COLLEGE OF MEDICINE · PI Brendan Lee, Dongsu Park · 2022 to 2026
$3.3M
WNT1 Function in Stem Cells in Osteogenesis Imperfecta and Craniofacial-Skeletal TissuesR01DE031162 · NIDCR · BAYLOR COLLEGE OF MEDICINE · PI LEE, BRENDAN, PARK, DONGSU · 2021 to 2025
$2.9M
Defining periosteal skeletal stem cells and novel migration mechanisms in bone regeneration and repair in vivoR01AR072018 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI PARK, DONGSU · 2018 to 2023
$2.1M
A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclastsR61AR078073 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MISHINA, YUJI, PARK, DONGSU · 2020 to 2021
$694k
A new model for spatio-temporal coupling of bone formation and bone resorption governed by osteoclastsR33AR078073 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MISHINA, YUJI, PARK, DONGSU · 2023 to 2023
$393k
Diffuse microdamage in bone: Direct repair without remodelingR21AR060445 · NIAMS · CITY COLLEGE OF NEW YORK · PI SCHAFFLER, MITCHELL B · 2011 to 2012
$371k
NIAMS NIH HHS 1R01AR072018NIAMS NIH HHS R01 AR072018NIAMS NIH HHS R33 AR078073NIAMS NIH HHS R61AR078073NIAMS NIH HHS T32DK060445NIDCR NIH HHS R01 DE031162NIDCR NIH HHS R01 DE031288
6 · The paper itself

Abstract

Dental pulp stem cells (DPSCs) have garnered significant interest in dental research for their unique characteristics and potential in tooth development and regeneration. While there were many studies to define their stem cell-like characteristics and osteogenic differentiation functions that are considered ideal candidates for regenerating damaged dental pulp tissue, how endogenous DPSCs respond to dental pulp injury and supply new dentin-forming cells has not been extensively investigated in vivo. Here, we review the recent progress in identity, function, and regulation of endogenous DPSCs and their clinical potential for pulp injury and regeneration. In addition, we discuss current advances in new mouse models, imaging techniques, and its practical uses and limitations in the analysis of DPSCs in pulp injury and regeneration in vivo.

Indexed as

Dental pulpMesenchymal

Identifiers

PMID37718901
PMCPMC10509030
OpenAlexW4386560421

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.