Evidence map›Paper›PMID 37719461›Full record

ArticleFrontiers in physiology2023

Mechanical stimuli such as shear stress and piezo1 stimulation generate red blood cell extracellular vesicles.

Gurneet S Sangha, Callie M Weber, Ryan M Sapp, Saini Setua, Kiruphagaran Thangaraju, Morgan Pettebone, Stephen C Rogers, Allan Doctor, Paul W Buehler, Alisa M Clyne

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. RYR1Journal of translational medicine · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Erythrocytes as a Source of Exerkines.International journal of molecular sciences · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Biomimetic erythrocyte-based drug delivery systems for organ-targeted therapy.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Gurneet S SanghaFischell Department of Bioengineering, University of Maryland, College Park, MD, United States.
Callie M WeberFischell Department of Bioengineering, University of Maryland, College Park, MD, United States.
Ryan M SappFischell Department of Bioengineering, University of Maryland, College Park, MD, United States.
Saini SetuaDepartment of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD, United States.
Kiruphagaran ThangarajuDepartment of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD, United States.
Morgan PetteboneFischell Department of Bioengineering, University of Maryland, College Park, MD, United States.
Stephen C RogersDepartment of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD, United States.
Allan DoctorDepartment of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD, United States.
Paul W BuehlerDepartment of Pediatrics, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD, United States.
Alisa M ClyneFischell Department of Bioengineering, University of Maryland, College Park, MD, United States.
University of Maryland, Baltimore · USUniversity of Maryland, College Park · US

Funding

Red blood cell ATP export and transfusion in sepsisR01HL161071 · NHLBI · DUKE UNIVERSITY · PI Allan Doctor, TIMOTHY J MCMAHON · 2023 to 2026
$2.7M
The effect of laminar and disturbed flow on endothelial glucose metabolismR01HL140239 · NHLBI · UNIV OF MARYLAND, COLLEGE PARK · PI MORSS CLYNE, ALISA S · 2018 to 2022
$1.9M
American Heart Association-American Stroke Association 916512NHLBI NIH HHS R01 HL140239NHLBI NIH HHS R01 HL161071
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

exosomesextracellular vesiclespiezo1red blood cellsshear stress

Identifiers

PMID37719461
PMCPMC10502313
OpenAlexW4386329986

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.