Evidence map›Paper›PMID 37721005›Full record

ReviewAmerican journal of physiology. Cell physiology2023

Signaling circuits and the apical extracellular matrix in aging: connections identified in the nematode

Hannah Reich, Cathy Savage-Dunn

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Cell physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hannah ReichDepartment of Biology, Queens College, City University of New York, Flushing, New York, United States.
Cathy Savage-DunnDepartment of Biology, Queens College, City University of New York, Flushing, New York, United States.ORCID 0000-0002-3457-0509
Queens College, CUNY · US

Funding

Regulation of Metabolism by C. Elegans DBL-1/BMP SignalingR15GM112147 · NIGMS · QUEENS COLLEGE · PI SAVAGE-DUNN, CATHY · 2015 to 2019
$832k
Multi-Omic Analysis of BMP-Insulin Signaling Crosstalk in Lipid Metabolism during AgingR21AG075315 · NIA · QUEENS COLLEGE · PI RONGO, CHRISTOPHER G, SAVAGE-DUNN, CATHY · 2022 to 2023
$456k
NIA NIH HHS R21 AG075315NIGMS NIH HHS R15 GM112147
6 · The paper itself

Abstract

Numerous conserved signaling pathways play critical roles in aging, including insulin/IGF-1, TGF-β, and Wnt pathways. Some of these pathways also play prominent roles in the formation and maintenance of the extracellular matrix. The nematode

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAgingAnimalsLongevityWnt Signaling PathwayCaenorhabditis elegans ProteinsagingCaenorhabditis eleganscell signalingcuticleextracellular matrix

Identifiers

PMID37721005
PMCPMC10861026
OpenAlexW4386817899

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.