Evidence map›Paper›PMID 37722684›Full record

ReviewAnnual review of genetics2023

Manipulating the Destiny of Wild Populations Using CRISPR.

Robyn Raban, John M Marshall, Bruce A Hay, Omar S Akbari

Abstract readReview
In one paragraph

Review in Annual review of genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Engineering drive-selection balance for localized population suppression with neutral dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Eliminating malaria vectors with precision-guided sterile males.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robyn RabanDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, California, USA; email: oakbari@ucsd.edu.
John M MarshallDivisions of Epidemiology and Biostatistics, School of Public Health, University of California, Berkeley, California, USA.
Bruce A HayDivision of Biology and Biological Engineering (BBE), California Institute of Technology, Pasadena, California, USA.
Omar S AkbariDepartment of Cell and Developmental Biology, School of Biological Sciences, University of California, San Diego, La Jolla, California, USA; email: oakbari@ucsd.edu.

Funding

The olfactory basis of locating nectar sugar sources in Aedes aegypti mosquitoesR01AI148300 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Ronald Jason Pitts · 2021 to 2026
$4.1M
Olfactory modulation of color vision and behavior in mosquitoesR01AI175152 · NIAID · UNIVERSITY OF WASHINGTON · PI Omar Sultan Akbari, Jeffrey A Riffell · 2023 to 2026
$3.2M
Development of synthetic viral circuitry to regulate viruses in mosquito disease vectorsDP2AI152071 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2019 to 2019
$2.4M
Precision guided SIT for the control of vector-borne diseaseR01AI151004 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AKBARI, OMAR SULTAN · 2020 to 2024
$2.3M
Public Engagement for Gene Drive TechnologyR01TR003514 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BLOSS, CINNAMON S · 2020 to 2023
$1.8M
Development of synthetic gene drives using small moleculesR01GM132825 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI AKBARI, OMAR SULTAN, CHOUDHARY, AMIT · 2019 to 2022
$1.4M
NCATS NIH HHS R01 TR003514NIAID NIH HHS DP2 AI152071NIAID NIH HHS R01 AI148300NIAID NIH HHS R01 AI151004NIAID NIH HHS R01 AI175152NIGMS NIH HHS R01 GM132825
6 · The paper itself

Abstract

Genetic biocontrol aims to suppress or modify populations of species to protect public health, agriculture, and biodiversity. Advancements in genome engineering technologies have fueled a surge in research in this field, with one gene editing technology, CRISPR, leading the charge. This review focuses on the current state of CRISPR technologies for genetic biocontrol of pests and highlights the progress and ongoing challenges of using these approaches.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene EditingGenomeCRISPRgene drivegenetic biocontrolhomingpopulation modificationpopulation suppression

Identifiers

PMID37722684
PMCPMC11064769

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.