ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2024
Reduced risk of de novo Barrett esophagus after bariatric surgery: a national database study.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 4 citations in OpenAlex.
- Metabolic and Bariatric Surgery vs. Dietary Counseling in Adults with Severe Obesity: Risk of De Novo Malignancy in a Propensity-Matched Multicentered Real-World Analysis.Obesity surgery · 2026Article
- Preoperative hypoalbuminemia and surgical complications in benign minimally invasive hysterectomy.Surgical endoscopy · 2026Article
- International Federation for Surgery for Obesity and Metabolic Disorders Position Statement on the role of Upper Gastrointestinal Endoscopy Before and After Metabolic Bariatric Surgery.Obesity surgery · 2025Article
- Gastroesophageal reflux disease and the phantom of Barrett's esophagus after most-often-used bariatric procedures: are future investigations necessary?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025Review
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8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundBariatric surgery is an effective treatment for obesity and may decrease the morbidity and mortality of obesity-associated cancers.
objectiveWe investigated the risk of a new diagnosis of Barrett esophagus (BE) following bariatric surgery compared to screening colonoscopy controls.
settingLarge national database including patients who received care in inpatient, outpatient, and specialty care services.
methodsA national healthcare database (TriNetX, LLC) was used for this analysis. Cases included adults (aged ≥18 yr) who had undergone either sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB). Controls included adults undergoing screening colonoscopy and an esophagoduodenoscopy on the same day and had never undergone bariatric surgery. Cases and controls were propensity-matched for confounders. The risk of de novo diagnosis of BE at least 1 year after bariatric surgery was compared between cases and controls. Secondary analyses examined the effect of bariatric surgery on metabolic outcomes such as weight loss and body mass index (BMI). The risk of de novo diagnosis of BE in SG was compared with RYGB. Odds ratios (OR) and 95% CI were used to report on these associations.
resultsIn the propensity-matched analysis, patients who had undergone a bariatric surgical procedure showed a significantly reduced risk of de novo BE when compared with screening colonoscopy controls (.67 [.48, .94]). There was substantial reduction in weight and BMI in the bariatric surgery group when compared with baseline. There was no significant difference in de novo BE diagnosis between the propensity-matched SG and RYGB groups (.77 [.5, 1.2]).
conclusionPatients who underwent bariatric surgery (RYGB or SG) had a lower risk of being diagnosed with BE compared with screening colonoscopy controls who did not receive bariatric surgery. This effect appears to be largely mediated by reduction in weight and BMI.
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