Evidence map›Paper›PMID 37725039›Full record

ArticleInflammatory bowel diseases2024

Predictors of Hospital-related Outcomes of COVID-19 Infection in Patients With Inflammatory Bowel Disease in the Early Pandemic Phase: A Nationwide Inpatient Database Survey.

Khadija Naseem, Abdullah Sohail, Vu Quang Nguyen, Ahmad Khan, Gregory Cooper, Bret Lashner, Jeffry Katz, Fabio Cominelli, Miguel Regueiro, Emad Mansoor

Abstract read
In one paragraph

Article in Inflammatory bowel diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Twenty-Five-Year Trends in Mortality Associated withMedical sciences (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Khadija NaseemCleveland Clinic Foundation, Cleveland, OH, USA.ORCID 0009-0009-9400-4451
Abdullah SohailThe University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Vu Quang NguyenCase Western Reserve University, Cleveland, OH, USA.
Ahmad KhanCase Western Reserve University, Cleveland, OH, USA.
Gregory CooperCase Western Reserve University, Cleveland, OH, USA.
Bret LashnerCleveland Clinic Foundation, Cleveland, OH, USA.
Jeffry KatzCase Western Reserve University, Cleveland, OH, USA.
Fabio CominelliCase Western Reserve University, Cleveland, OH, USA.ORCID 0000-0002-1571-1548
Miguel RegueiroCleveland Clinic Foundation, Cleveland, OH, USA.ORCID 0000-0002-7681-8111
Emad MansoorCase Western Reserve University, Cleveland, OH, USA.

Funding

The Cleveland Digestive Diseases Research Core Center (DDRCC)P30DK097948 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Fabio Cominelli · 2015 to 2026
$15.6M
6 · The paper itself

Abstract

backgroundPatients with inflammatory bowel disease (IBD) are at higher risk for severe COVID-19 infection. However, most studies are single-center, and nationwide data in the United States are lacking. This study aimed to investigate hospital-related outcomes and predictors of these outcomes in patients with IBD and COVID-19 infection.

methodsThe National Inpatient Sample and National Readmission database were queried for all the patient hospitalizations with IBD with concurrent COVID-19 in the study group and non-COVID-19 related hospitalizations in the control group. For patients under 18 years, elective and trauma-related hospitalizations were excluded. Primary outcomes included mortality, septic shock, mechanical ventilation, and intensive care utilization. Secondary outcomes included length of stay and total hospitalization costs.

resultsFrom this query, 8865 adult patients with IBD and COVID-19 were identified. These patients were relatively older (62.8 vs 57.7 years, P < .01), and the majority were females (52.1% with COVID-19 vs 55.2% without COVID-19). Patients with IBD and COVID-19 had higher mortality (12.24% vs 2.55%; P < .01), increased incidence of septic shock (7.9% vs 4.4%; P < .01), mechanical ventilation (11.5% vs 3.7%; P < .01), and intensive care utilization (12% vs 4.6%; P < .01). These patients also had higher mean length of stay (8.28 days vs 5.47 days; P < .01) and total hospitalization costs ($21 390 vs $16 468; P < .01) than those without COVID-19 infection.

conclusionsPatients with IBD and COVID-19 have worse outcomes, with a higher incidence of severe COVID-19 disease, leading to higher mortality rates, longer lengths of stay, and increased total hospitalization costs. Encouraging preventive health measures and treating promptly with advanced COVID-19 therapies may improve outcomes and decrease the healthcare burden.

Indexed as

COVID-19Databases, FactualHospitalizationInflammatory Bowel DiseasesLength of StaySARS-CoV-2AdultAgedFemaleHospital CostsHospital MortalityHumansInpatientsMaleMiddle AgedRespiration, Artificialinflammatory bowel diseasemean length of staymortalityresource utilizationseverity of COVID-19 infection

Identifiers

PMID37725039
PMCPMC11519050

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.