Evidence map›Paper›PMID 37726379›Full record

ArticleScientific reports2023

In-vivo detection of white adipose tissue browning: a multimodality imaging approach.

Leah R Holmes, John C Garside, Jonathan Frank, Eric Livingston, Jonas Snyder, Nada Abu Khalaf, Hong Yuan, Rosa T Branca

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. White adipose tissue uptake onRadiology case reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Leah R HolmesDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
John C GarsideDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jonathan FrankBiomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Eric LivingstonBiomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jonas SnyderDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Nada Abu KhalafDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Hong YuanBiomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Rosa T BrancaDepartment of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. rtbranca@unc.edu.
University of North Carolina at Chapel Hill · USImaging Center · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ian Michael Carroll · 1999 to 2026
$31.6M
Enabling accurate identification and quantification of brown adipose tissue mass by xenon enhanced computed tomographyR01DK123206 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BRANCA, ROSA TAMARA · 2020 to 2021
$866k
Small Animal PET/CT for Preclinical Imaging ResearchS10OD023611 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, ZIBO · 2017 to 2017
$835k
NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK123206NIH HHS S10 OD023611
6 · The paper itself

Abstract

Detection and differentiation of brown fat in humans poses several challenges, as this tissue is sparse and often mixed with white adipose tissue. Non-invasive detection of beige fat represents an even greater challenge as this tissue is structurally and functionally more like white fat than brown fat. Here we used positron emission tomography with

Indexed as

AdipocytesFluorodeoxyglucose F18Adipose Tissue, WhiteAnimalsHumansMiceNorepinephrinePerfusionFluorodeoxyglucose F18Norepinephrine

Identifiers

PMID37726379
PMCPMC10509182
OpenAlexW4386843975

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.