Evidence map›Paper›PMID 37735143›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

Shape Anisotropy-Governed High-Performance Nanomagnetosol for In Vivo Magnetic Particle Imaging of Lungs.

Saumya Nigam, Jeotikanta Mohapatra, Ashley V Makela, Hanaan Hayat, Jessi Mercedes Rodriguez, Aixia Sun, Elizabeth Kenyon, Nathan A Redman, Dana Spence, George Jabin and 12 more

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Biosafety of micron-sized FeJournal of thoracic disease · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Machine Learning and Deep Learning Applications in Magnetic Particle Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  9. Article
  10. Article
  11. The Application of Nanovaccines in Autoimmune Diseases.International journal of nanomedicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Saumya NigamPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Jeotikanta MohapatraDepartment of Physics, The University of Texas at Arlington, Arlington, TX, 76019, USA.
Ashley V MakelaInstitute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI, 48824, USA.
Hanaan HayatPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Jessi Mercedes RodriguezPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Aixia SunPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Elizabeth KenyonPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Nathan A RedmanInstitute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI, 48824, USA.
Dana SpenceInstitute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI, 48824, USA.
George JabinDepartment of Physics, The University of Texas at Arlington, Arlington, TX, 76019, USA.
Bin GuDepartment of Obstetrics, Gynecology and Reproductive Sciences, College of Human Medicine, Michigan State University, East Lansing, MI, 48824, USA.
Mohamed AshryPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Lorenzo F SemperePrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.
Arijit MitraDepartment of Materials Science and Engineering, National Cheng Kung University, Tainan City, 701, Taiwan.
Jinxing LiInstitute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI, 48824, USA.
Jiahui ChenDepartment of Mathematics, College of Natural Science, Michigan State U, niversity, East Lansing, MI, 48824, USA.
Guo-Wei WeiDepartment of Mathematics, College of Natural Science, Michigan State U, niversity, East Lansing, MI, 48824, USA.
Steven BolinDepartment of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, 48824, USA.
Brett EtchebarneOsteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, 48824, USA.
J Ping LiuDepartment of Physics, The University of Texas at Arlington, Arlington, TX, 76019, USA.
Christopher H ContagInstitute for Quantitative Health Science and Engineering (IQ), Michigan State University, East Lansing, MI, 48824, USA.
Ping WangPrecision Health Program, Michigan State University, East Lansing, MI, 48824, USA.

Funding

Image-Guided Intraductal Ablative Procedure for Primary Prevention of Breast CancerR01CA258314 · NCI · MICHIGAN STATE UNIVERSITY · PI Lorenzo Sempere · 2022 to 2026
$2.8M
AI-based platform for predicting emerging vaccine-escape variants and designing mutation-proof antibodiesR01AI164266 · NIAID · UNIVERSITY OF GEORGIA · PI Guowei Wei, YONG-HUI ZHENG · 2022 to 2026
$2.7M
In vivo tracking of inhaled ACE2 targeting theranostic nanodrugs delivery to the lungs using magnetic particle imagingR21AI159928 · NIAID · MICHIGAN STATE UNIVERSITY · PI WANG, PING · 2021 to 2021
$430k
NCI NIH HHS R01 CA258314NIAID NIH HHS R01 AI164266NIAID NIH HHS R21 AI159928
6 · The paper itself

Abstract

Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus disease 2019 (COVID-19) has shown extensive lung manifestations in vulnerable individuals, putting lung imaging and monitoring at the forefront of early detection and treatment. Magnetic particle imaging (MPI) is an imaging modality, which can bring excellent contrast, sensitivity, and signal-to-noise ratios to lung imaging for the development of new theranostic approaches for respiratory diseases. Advances in MPI tracers would offer additional improvements and increase the potential for clinical translation of MPI. Here, a high-performance nanotracer based on shape anisotropy of magnetic nanoparticles is developed and its use in MPI imaging of the lung is demonstrated. Shape anisotropy proves to be a critical parameter for increasing signal intensity and resolution and exceeding those properties of conventional spherical nanoparticles. The 0D nanoparticles exhibit a 2-fold increase, while the 1D nanorods have a > 5-fold increase in signal intensity when compared to VivoTrax. Newly designed 1D nanorods displayed high signal intensities and excellent resolution in lung images. A spatiotemporal lung imaging study in mice revealed that this tracer offers new opportunities for monitoring disease and guiding intervention.

Indexed as

Magnetite NanoparticlesNanoparticlesAnimalsAnisotropyDiagnostic ImagingMagnetic PhenomenaMagnetic Resonance ImagingMagneticsMiceMagnetite Nanoparticlesaerosolslung imagingmagnetic particle imagingnanorodssuperparamagnetic iron oxide nanoparticles

Identifiers

PMID37735143
PMCPMC10842459

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.