Evidence map›Paper›PMID 37735265›Full record

ArticleNature biotechnology2024

A DNA nanodevice for mapping sodium at single-organelle resolution.

Junyi Zou, Koushambi Mitra, Palapuravan Anees, Daphne Oettinger, Joseph R Ramirez, Aneesh Tazhe Veetil, Priyanka Dutta Gupta, Rajini Rao, Jayson J Smith, Paschalis Kratsios and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nature biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. A nucleic acid labeling chemistry reveals surface DNA on exosomes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. A nucleic acid labeling chemistry reveals surface DNA on exosomes.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Metal Ion Signaling in Biomedicine.Chemical reviews · 2025
    Review
  15. Article
  16. Review
  17. Quantitative Chemical Imaging of Organelles.Accounts of chemical research · 2024
    Article
  18. DNA nanodevices map intracellular ions.Nature biotechnology · 2024
    Article
  19. The ion channels of endomembranes.Physiological reviews · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Junyi ZouDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-5005-737X
Koushambi MitraDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-4325-453X
Palapuravan AneesDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Daphne OettingerDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Joseph R RamirezDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Aneesh Tazhe VeetilDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Priyanka Dutta GuptaDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Rajini RaoDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jayson J SmithNeuroscience Institute, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-8525-7873
Paschalis KratsiosNeuroscience Institute, The University of Chicago, Chicago, IL, USA.
Yamuna KrishnanDepartment of Chemistry, The University of Chicago, Chicago, IL, USA. yamuna@uchicago.edu.ORCID http://orcid.org/0000-0001-5282-8852
University of Chicago · USJohns Hopkins University · US

Funding

Intracellular Electrophysiology: An electrochemical atlas of organellesDP1GM149751 · NIGMS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2022 to 2025
$5.7M
Mechanism and function of intracellular sodium-proton exchangersR01GM147197 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI KRISHNAN, YAMUNA, MIRSHAHI, TOORAJ · 2022 to 2025
$2.4M
Calcium homeostasis in organellesR01NS112139 · NINDS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2020 to 2024
$1.8M
Mechanisms that alter Potassium channel trafficking in arrhythmiasR21HL161825 · NHLBI · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2022 to 2023
$448k
A mechanism of lysosomal Calcium entryR21NS114428 · NINDS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2019 to 2020
$408k
Human Frontier Science Program (HFSP) RGP0032/2022NHLBI NIH HHS R21 HL161825NIGMS NIH HHS DP1 GM149751NIGMS NIH HHS R01 GM147197NINDS NIH HHS R01 NS112139NINDS NIH HHS R21 NS114428United States Department of Defense | United States Air Force | AFMC | Air Force Office of Scientific Research (AF Office of Scientific Research) FA9550-19-0003U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R21HL161825-01A1U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) 1R01GM147197-01U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) DP1GM149751U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 1R01NS112139-01A1U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) 1R21NS114428-01
6 · The paper itself

Abstract

Cellular sodium ion (Na

Indexed as

Caenorhabditis elegansDNASodiumAnimalsEndosomesHomeostasisHumansLysosomesOrganellesDNASodium

Identifiers

PMID37735265
PMCPMC11004682
OpenAlexW4386923863

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.