Evidence mapPaperPMID 37735467Full record

ArticleNature communications2023

DeepSlice: rapid fully automatic registration of mouse brain imaging to a volumetric atlas.

Harry Carey, Michael Pegios, Lewis Martin, Chris Saleeba, Anita J Turner, Nicholas A Everett, Ingvild E Bjerke, Maja A Puchades, Jan G Bjaalie, Simon McMullan

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Region- and Layer-Specific Glutamatergic Synapse Development in the Nascent Cortical Hierarchy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  11. Mapping brain-wide activity networks: brainways as a tool for neurobiological discovery.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  12. Article
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  14. A genetically defined pontine nucleus essential for ingestion in mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Harry CareyMacquarie Medical School, Faculty of Medicine, Health & Human Sciences, Macquarie University, Marsfield, NSW, Australia.
Michael PegiosMacquarie Medical School, Faculty of Medicine, Health & Human Sciences, Macquarie University, Marsfield, NSW, Australia.
Lewis MartinOpenBench, San Francisco, CA, USA.
Chris SaleebaMacquarie Medical School, Faculty of Medicine, Health & Human Sciences, Macquarie University, Marsfield, NSW, Australia.
Anita J TurnerMacquarie Medical School, Faculty of Medicine, Health & Human Sciences, Macquarie University, Marsfield, NSW, Australia.ORCID http://orcid.org/0000-0001-9580-3890
Nicholas A EverettSchool of Psychology, University of Sydney, Camperdown, NSW, Australia.
Ingvild E BjerkeDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-2926-6836
Maja A PuchadesDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-4536-8197
Jan G BjaalieDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0001-7899-906X
Simon McMullanMacquarie Medical School, Faculty of Medicine, Health & Human Sciences, Macquarie University, Marsfield, NSW, Australia. simon.mcmullan@mq.edu.au.ORCID http://orcid.org/0000-0002-9854-1029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Registration of data to a common frame of reference is an essential step in the analysis and integration of diverse neuroscientific data. To this end, volumetric brain atlases enable histological datasets to be spatially registered and analyzed, yet accurate registration remains expertise-dependent and slow. In order to address this limitation, we have trained a neural network, DeepSlice, to register mouse brain histological images to the Allen Brain Common Coordinate Framework, retaining registration accuracy while improving speed by >1000 fold.

Indexed as

AscomycotaAnimalsBrainMiceNeural Networks, ComputerNeuroimagingReading Frames

Identifiers

PMID37735467
PMCPMC10514056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.