ArticleJournal of cachexia, sarcopenia and muscle2023
Impact of sarcopenia on the survival of patients undergoing liver transplantation for decompensated liver cirrhosis.
Article in Journal of cachexia, sarcopenia and muscle, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Effect of sarcopenia on the survival of patients undergoing liver transplantation: a meta-analysis.Surgery today · 2025Pooled it
- Article
- Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1-year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors.Oncology letters · 2026Article
- Current management strategies for sarcopenia and frailty in cirrhosis: Missing link in transplant candidacy.World journal of hepatology · 2026Review
- Pre-transplant physical performance, muscle quality, and body composition as predictors of post-liver transplant outcomes: a retrospective cohort study.European journal of medical research · 2026Article
- Development and validation of a nomogram for identifying prevalent sarcopenia in Chinese patients with Cardiovascular-Kidney-Metabolic Syndrome.Frontiers in public health · 2026Article
- Combination of Frailty and Sarcopenia Predicts Peri-operative Outcomes in Patients Undergoing Liver Transplantation: Analysis of the National Inpatient Sample.Digestive diseases and sciences · 2025Article
- Machine learning predicts post-transplant muscle loss in hepatocellular carcinoma patients without sarcopenia.BMC cancer · 2025Article
- Creatinine-to-Cystatin C Ratio Combined with FIB-4 and ELF for Noninvasive Fibrosis Assessment in MASLD.International journal of molecular sciences · 2025Article
- Synergistic Integration of Multimodal Metabolic and Bariatric Interventions Transforming Transplant Care.Journal of clinical medicine · 2025Review
- A short-term predictive model for disease progression in acute-on-chronic liver failure: integrating spectral CT extracellular liver volume and clinical characteristics.BMC medical imaging · 2025Article
- A predictive model based on the GLIM diagnosis for malnutrition in older adult heart failure patients.Frontiers in nutrition · 2025Article
- Sarcopenia in liver transplantation: A comprehensive bibliometric study of current research trends and future directions.Open life sciences · 2025Article
- Impact of chest computed tomography-determined low skeletal muscle mass on the survival of patients with acute heart failure.Frontiers in cardiovascular medicine · 2025Article
- Frailty after Liver Transplantation: A Complex Unexplored Issue.Journal of clinical medicine · 2024Review
- Impact of sarcopenia on the survival of patients undergoing liver transplantation for decompensated liver cirrhosis.Journal of cachexia, sarcopenia and muscle · 2023Article
- A brief review of sarcopenia and frailty in the early post-liver transplant period.Clinical liver diseaseArticle
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPatients with decompensated cirrhosis (DC) are prone to skeletal muscle loss, namely, sarcopenia, before liver transplantation (LT). While sarcopenia is reportedly associated with adverse outcomes after LT, these findings are limited owing to mixed diseases and retrospective data. We investigated the association between sarcopenia and 1-year overall survival (OS) in patients with DC after LT and established and validated a prediction model for postoperative OS based on sarcopenia.
methodsOverall, 222 consecutive patients who underwent LT at our centre were registered between September 2020 and June 2022. Third lumbar spine skeletal muscle mass index was measured using computed tomography. Patients were divided into sarcopenia and non-sarcopenia groups according to the skeletal muscle mass index, and baseline data and postoperative outcomes were collected, compared and analysed. The primary outcome was the 1-year OS after LT. We established a dynamic nomogram of the OS predictive model.
resultsWe included 177 DC patients [mean (standard deviation) age, 50.2 ± 9.3 years; 52 women (29.4%)]; 73 (41.2%) had sarcopenia. The mean (standard deviation) body mass index was 22.6 ± 4.5 kg/m
conclusionsSarcopenia is associated with adverse outcomes after LT in patients with DC. High-risk patients should be classified by dynamic nomogram upon admission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.