Evidence mapPaperPMID 37736993Full record

ReviewTomography (Ann Arbor, Mich.)2023

Non-Calcified Coronary Artery Plaque on Coronary Computed Tomography Angiogram: Prevalence and Significance.

Bandar Alyami, Matthew Santer, Karthik Seetharam, Dhivya Velu, Eswar Gadde, Bansari Patel, Yasmin S Hamirani

Abstract readReview
In one paragraph

Review in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bandar AlyamiDepartment of Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-0736-3918
Matthew SanterDepartment of Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.ORCID 0009-0005-4889-7392
Karthik SeetharamDepartment of Cardiology, Heart and Vascular Institute, West Virginia University, Morgantown, WV 26506, USA.
Dhivya VeluDepartment of Cardiology, Heart and Vascular Institute, West Virginia University, Morgantown, WV 26506, USA.
Eswar GaddeDepartment of Medicine, West Virginia University, Charleston, WV 25304, USA.
Bansari PatelDepartment of Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506, USA.
Yasmin S HamiraniDepartment of Cardiology, Heart and Vascular Institute, West Virginia University, Morgantown, WV 26506, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to assess the prevalence of non-calcified plaque (NCP) on computed tomography angiography (CCTA) in symptomatic and asymptomatic individuals. In addition, we seek to compare plaque assessment on CCTA with intravascular ultrasound-virtual histology (IVUS-VH) and to assess the prognostic value of non-calcified plaques (NCPs).

backgroundThe CCTA can characterize coronary plaques and help quantify burden. Furthermore, it can provide additional prognostic information which can enable further risk stratification of patients.

methodsWe performed a broad comprehensive review of the current literature pertaining to CCTA and primarily isolated NCP in symptomatic and asymptomatic patients. In addition, our review included studies correlating plaque on CT with IVUS-VH.

conclusionsNCP is the initial precursor of calcified plaque and serves as a prominent marker of early coronary atherosclerosis. By detecting NCP during early stages, several measures can be implemented which can alter the evolutionary course of the underlying disease. This can potentially lead to a lower incidence of cardiovascular events.

Indexed as

Coronary VesselsTomography, X-Ray ComputedAngiographyHumansPrevalenceangiographycardiac CT calcium scorechest paincoronary computed tomographycoronary plaquessystematic review

Identifiers

PMID37736993
PMCPMC10514817

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.