A Brief Overview of the Toxic Sphingomyelinase Ds of Brown Recluse Spider Venom and Other Organisms and Simple Methods To Detect Production of Its Signature Cyclic Ceramide Phosphate.

Hannah Lachmayr, Alfred H Merrill

Erratum issuedOpen access · bronzeAbstract read

In one paragraph

Article in Molecular pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

3.1field-weighted citation impact, top 8% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

Toxins · 2026
Article
The bioactive sphingolipid playbook. A primer for the uninitiated as well as sphingolipidologists.Journal of lipid research · 2025
Review
Structural and Energetic Evidence Supports the Non-Covalent Phosphate Cyclization by the Class II Phospholipase D fromToxins · 2025
Article
Brown Spider Venom Phospholipases D: From Potent Molecules Involved in Pathogenesis of Brown Spider Bites to Molecular Tools for Studying Ectosomes, Ectocytosis, and Its Applications.Toxins · 2025
Review
Don't Be Surprised When These Surprise You: Some Infrequently Studied Sphingoid Bases, Metabolites, and Factors That Should Be Kept in Mind During Sphingolipidomic Studies.International journal of molecular sciences · 2025
Review

4 · The record

Corrections and comments

Erratum issued
Correction to "A Brief Overview of the Toxic Sphingomyelinase Ds of Brown Recluse Spider Venom and Other Organisms and Simple Methods To Detect Production of Its Signature Cyclic Ceramide Phosphate".2024

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hannah LachmayrSchool of Biological Sciences and the Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia.

Alfred H MerrillSchool of Biological Sciences and the Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia al.merrill@biosci.gatech.edu.

Georgia Institute of Technology · US

Funding

STEROL LIPIDSU54GM069338 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 2003 to 2013

$72.2M

NIGMS NIH HHS U54 GM069338

6 · The paper itself

Abstract

A special category of phospholipase D (PLD) in the venom of the brown recluse spider (

Indexed as

Phospholipase DSpidersSpider VenomsAnimalsCeramidesHumansPhosphatesPhosphoric Diester HydrolasesSphingomyelin PhosphodiesteraseCeramidesloxosceles venomPhosphatesPhospholipase DPhosphoric Diester HydrolasesSphingomyelin Phosphodiesterasesphingomyelin phosphodiesterase DSpider Venoms

Identifiers

PMID37739813

DOI10.1124/molpharm.123.000709

PMCPMC10877732

OpenAlexW4386948420

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.