Evidence map›Paper›PMID 37739992›Full record

ArticleScientific reports2023

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

Michael J Davis, Jorge A Castorena-Gonzalez, Scott D Zawieja

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Pacemaking in the lymphatic system.The Journal of physiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Regulation of Collecting Lymphatic Vessel Contractile Function by TRPV4 Channels.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael J DavisDepartment of Medical Pharmacology and Physiology, University of Missouri School of Medicine, One Hospital Drive, MA415 Medical Sciences Building, Columbia, MO, 65212, USA. davismj@health.missouri.edu.
Jorge A Castorena-GonzalezDepartment of Pharmacology, Tulane University School of Medicine, New Orleans, LA, 70112, USA.
Scott D ZawiejaDepartment of Medical Pharmacology and Physiology, University of Missouri School of Medicine, One Hospital Drive, MA415 Medical Sciences Building, Columbia, MO, 65212, USA.
University of Missouri Hospital · USTulane University · US

Funding

Lymphatic pacemaking and pumping in lymphedema: function, dysfunction, and rescueR01HL122578 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DAVIS, MICHAEL JOHN · 2015 to 2023
$4.1M
KATP channels and lymphatic dysfunction in Cantu SyndromeR01HL141107 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DAVIS, MICHAEL JOHN · 2018 to 2021
$1.5M
The Regulation of Lymphatic Muscle Cell Pacemaking by Intracellular Calcium SignalsR00HL143198 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI ZAWIEJA, SCOTT D. · 2021 to 2023
$747k
NHLBI NIH HHS R00 HL143198NHLBI NIH HHS R01 HL122578NHLBI NIH HHS R01 HL141107
6 · The paper itself

Abstract

We previously identified two isoforms of T-type, voltage-gated calcium (Ca

Indexed as

Calcium Channels, T-TypeLymphatic VesselsAnimalsCalcium Channels, L-TypeCalcium, DietaryMiceMusclesCalcium Channels, L-TypeCalcium Channels, T-TypeCalcium, Dietary

Identifiers

PMID37739992
PMCPMC10516884
OpenAlexW4386951764

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.