Evidence map›Paper›PMID 37743390›Full record

ArticleScientific reports2023

The potential role of miRNAs and regulation of their expression in the development of mare endometrial fibrosis.

Anna Wójtowicz, Tomasz Molcan, Karolina Lukasik, Ewelina Żebrowska, Klaudia Pawlina-Tyszko, Artur Gurgul, Tomasz Szmatoła, Monika Bugno-Poniewierska, Graca Ferreira-Dias, Dariusz J Skarzynski and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Anna WójtowiczDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Tomasz MolcanMolecular Biology Laboratory, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Karolina LukasikDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Ewelina ŻebrowskaDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Klaudia Pawlina-TyszkoDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Cracow, Poland.
Artur GurgulDepartment of Animal Reproduction, Anatomy and Genomics, The University of Agriculture in Krakow, Cracow, Poland.
Tomasz SzmatołaDepartment of Animal Molecular Biology, National Research Institute of Animal Production, Cracow, Poland.
Monika Bugno-PoniewierskaDepartment of Animal Reproduction, Anatomy and Genomics, The University of Agriculture in Krakow, Cracow, Poland.
Graca Ferreira-DiasFaculty of Veterinary Medicine, CIISA - Center for Interdisciplinary Research in Animal Health, University of Lisbon, Lisbon, Portugal.
Dariusz J SkarzynskiDepartment of Reproduction and Clinic of Farm Animals, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
Anna Szóstek-MioduchowskaDepartment of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland. a.szostek-mioduchowska@pan.olsztyn.pl.
Polish Academy of Sciences · PLUniversity of Agriculture in Krakow · PLInstitute of Animal Reproduction and Food Research · PLNational Research Institute of Animal Production · PLUniversity of Lisbon · PTWroclaw University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mare endometrial fibrosis (endometrosis), is one of the main causes of equine infertility. Despite the high prevalence, both ethology, pathogenesis and the nature of its progression remain poorly understood. Recent studies have shown that microRNAs (miRNAs) are important regulators in multiple cellular processes and functions under physiological and pathological circumstances. In this article, we reported changes in miRNA expression at different stages of endometrosis and the effect of transforming growth factor (TGF)-β1 on the expression of the most dysregulated miRNAs. We identified 1, 26, and 5 differentially expressed miRNAs (DEmiRs), in categories IIA (mild fibrosis), IIB (moderate fibrosis), and III (severe fibrosis) groups compared to category I (no fibrosis) endometria group, respectively (P

Indexed as

MicroRNAsUterine DiseasesAnimalsCytokinesEndometriumFemaleFibroblastsHorsesHumansCytokinesMicroRNAs

Identifiers

PMID37743390
PMCPMC10518347
OpenAlexW4386997909

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.