Evidence map›Paper›PMID 37744234›Full record

ArticlePeerJ2023

Modelling and analysis of the complement system signalling pathways: roles of C3, C5a and pro-inflammatory cytokines in SARS-CoV-2 infection.

Didar Murad, Rehan Zafar Paracha, Muhammad Tariq Saeed, Jamil Ahmad, Ammar Mushtaq, Maleeha Humayun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Didar MuradSchool of Interdisciplinary Engineering and Sciences/Department of Sciences, National University of Science and Technology, Islamabad, Pakistan.
Rehan Zafar ParachaSchool of Interdisciplinary Engineering and Sciences/Department of Sciences, National University of Science and Technology, Islamabad, Pakistan.
Muhammad Tariq SaeedSchool of Interdisciplinary Engineering and Sciences/Department of Sciences, National University of Science and Technology, Islamabad, Pakistan.
Jamil AhmadDepartment of Computer Science and Information Technology, University of Malakand, Chakdara, Malakand, Pakistan.
Ammar MushtaqSchool of Interdisciplinary Engineering and Sciences/Department of Sciences, National University of Science and Technology, Islamabad, Pakistan.
Maleeha HumayunSchool of Interdisciplinary Engineering and Sciences/Department of Sciences, National University of Science and Technology, Islamabad, Pakistan.
University of Malakand · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system is an essential part of innate immunity. It is activated by invading pathogens causing inflammation, opsonization, and lysis

Indexed as

COVID-19CytokinesComplement Membrane Attack ComplexComplement System ProteinsHumansSARS-CoV-2Complement Membrane Attack ComplexComplement System ProteinsCytokinesBiological regulatory network (BRN)C3C5aComplement systemModel checker (NuSMV)PICytsQualitative modellingRené ThomasSARS-CoV-2SMBioNet

Identifiers

PMID37744234
PMCPMC10517668
OpenAlexW4386891456

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.