Evidence map›Paper›PMID 37744827›Full record

ArticleACS omega2023

Anti-SpCas9 IgY Polyclonal Antibodies Production for CRISPR Research Use.

Esteban León, Valentina Ortiz, Alexander Pérez, Jair Téllez, Gonzalo J Díaz, María H Ramírez H, Luis E Contreras R

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Latest Findings in Immunoglobulin Y Technologies and Applications.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esteban LeónFacultad de Ciencias, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.
Valentina OrtizFacultad de Ciencias, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.
Alexander PérezFacultad de Ciencias, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.
Jair TéllezEscuela de Pregrado, Dirección Académica, Universidad Nacional de Colombia, 202017 sede La Paz, Colombia.ORCID https://orcid.org/0000-0001-6646-8069
Gonzalo J DíazFacultad de Medicina Veterinaria y de Zootecnia, Laboratorio de Toxicología, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.
María H Ramírez HFacultad de Ciencias, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.
Luis E Contreras RFacultad de Ciencias, Universidad Nacional de Colombia, 111311 Bogotá, Colombia.ORCID https://orcid.org/0000-0002-3448-3640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The CRISPR/Cas adaptative immune system has been harnessed as an RNA-guided, programmable genome editing tool, allowing for diverse biotechnological applications. The implementation of the system relies on the ability to detect the Cas9 protein in biological samples. This task is facilitated by employing antibodies, which exhibit several advantageous features and applications in the context of tropical neglected diseases. This study reports a one-month immunization scheme with the Cas9 protein from

Identifiers

PMID37744827
PMCPMC10515394

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.