Evidence map›Paper›PMID 37744913›Full record

ArticleFrontiers in microbiology2023

Genetic assessment of the effect of red yeast (

Shahrbanou Hosseini, Bertram Brenig, Sunattinee Winitchakorn, Chanidapha Kanmanee, Orranee Srinual, Wanaporn Tapingkae, Kesinee Gatphayak

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shahrbanou HosseiniMolecular Biology of Livestock and Molecular Diagnostics, Department of Animal Sciences, University of Goettingen, Göttingen, Germany.
Bertram BrenigMolecular Biology of Livestock and Molecular Diagnostics, Department of Animal Sciences, University of Goettingen, Göttingen, Germany.
Sunattinee WinitchakornDepartment of Animal and Aquatic Sciences, Chiang Mai University, Chiang Mai, Thailand.
Chanidapha KanmaneeDepartment of Animal and Aquatic Sciences, Chiang Mai University, Chiang Mai, Thailand.
Orranee SrinualDepartment of Animal and Aquatic Sciences, Chiang Mai University, Chiang Mai, Thailand.
Wanaporn TapingkaeDepartment of Animal and Aquatic Sciences, Chiang Mai University, Chiang Mai, Thailand.
Kesinee GatphayakDepartment of Animal and Aquatic Sciences, Chiang Mai University, Chiang Mai, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxic fungal species produce hazardous substances known as mycotoxins. Consumption of mycotoxin contaminated feed and food causes a variety of dangerous diseases and can even lead to death of animals and humans, raising global concerns for adverse health effects. To date, several strategies have been developed to counteract with mycotoxin contamination. Red yeast as a novel biological dietary agent is a promising strategy to eliminate mycotoxicity in living organisms. Poultry are most susceptible animals to mycotoxin contamination, as they are fed a mixture of grains and are at higher risk of co-exposure to multiple toxic fungal substances. Therefore, this study investigated the genetic mechanism underlying long-term feeding with red yeast supplementation in interaction with multiple mycotoxins using transcriptome profiling (RNA_Seq) in the liver of laying hens. The results showed a high number of significantly differentially expressed genes in liver of chicken fed with a diet contaminated with mycotoxins, whereas the number of Significantly expressed genes was considerably reduced when the diet was supplemented with red yeast. The expression of genes involved in the phase I (

Indexed as

detoxificationfeed additivegene expressionlaying hensmycotoxinred yeastRNA sequencing

Identifiers

PMID37744913
PMCPMC10512063

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.