Evidence map›Paper›PMID 37745299›Full record

ArticleFrontiers in cell and developmental biology2023

Alternative splicing of a single exon causes a major impact on the affinity of

Shoichiro Ono, Eichi Watabe, Keita Morisaki, Kanako Ono, Hidehito Kuroyanagi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. The sole essential low molecular weight tropomyosin isoform ofbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shoichiro OnoDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, GA, United States.
Eichi WatabeLaboratory of Gene Expression, Graduate School of Biomedical Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Keita MorisakiDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, GA, United States.
Kanako OnoDepartments of Pathology and Cell Biology, Emory University School of Medicine, Atlanta, GA, United States.
Hidehito KuroyanagiLaboratory of Gene Expression, Graduate School of Biomedical Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Emory University · USTokyo Medical and Dental University · JPUniversity of the Ryukyus · JP

Funding

Regulation of actin dynamics during myofibril assemblyR01AR048615 · NIAMS · EMORY UNIVERSITY · PI ONO, SHOICHIRO · 2002 to 2021
$6.2M
NIAMS NIH HHS R01 AR048615
6 · The paper itself

Abstract

Tropomyosin is generally known as an actin-binding protein that regulates actomyosin interaction and actin filament stability. In metazoans, multiple tropomyosin isoforms are expressed, and some of them are involved in generating subpopulations of actin cytoskeleton in an isoform-specific manner. However, functions of many tropomyosin isoforms remain unknown. Here, we report identification of a novel alternative exon in the

Indexed as

actin-binding proteinscoiled-coilcytoskeletonmolecular dynamics simulationnematodes

Identifiers

PMID37745299
PMCPMC10512467
OpenAlexW4386522134

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.