Evidence map›Paper›PMID 37745713›Full record

SynthesisFrontiers in endocrinology2023

Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk.

Sean Bankier, Lingfei Wang, Andrew Crawford, Ruth A Morgan, Arno Ruusalepp, Ruth Andrew, Johan L M Björkegren, Brian R Walker, Tom Michoel

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

Sean BankierUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Lingfei WangDivision of Genetics and Genomics, The Roslin Institute, The University of Edinburgh, Edinburgh, United Kingdom.
Andrew CrawfordUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Ruth A MorganUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Arno RuusaleppDepartment of Cardiac Surgery, Tartu University Hospital, Tartu, Estonia.
Ruth AndrewUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Johan L M BjörkegrenClinical Gene Networks AB, Stockholm, Sweden.
Brian R WalkerUniversity/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom.
Tom MichoelComputational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.
The Queen's Medical Research Institute · GBUniversity of Edinburgh · GBGenomics (United Kingdom) · GBIcahn School of Medicine at Mount Sinai · USUniversity of Tartu · EE

Funding

Medical Research Council 1938124Wellcome Trust 107049/Z/15/ZWellcome Trust 206587/Z/17/Z
6 · The paper itself

Abstract

Genome-wide association meta-analysis (GWAMA) by the Cortisol Network (CORNET) consortium identified genetic variants spanning the

Indexed as

Cardiovascular DiseasesGlucocorticoidsTranscortinAdipose TissueGene Regulatory NetworksGenome-Wide Association StudyHeart Disease Risk FactorsHumansHydrocortisoneLiverReceptors, GlucocorticoidRisk FactorsGlucocorticoidsHydrocortisoneReceptors, GlucocorticoidSERPINA6 protein, humanTranscortincausal inferencecorticosteroid-binding globulincortisolgene networkssystems genetics

Identifiers

PMID37745713
PMCPMC10513085
OpenAlexW4386470002

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.