Evidence map›Paper›PMID 37746355›Full record

ReviewCureus2023

Individualizing Medicinal Therapy Post Heart Stent Implantation: Tailoring for Patient Factors.

Tamam Mohamad, Fnu Jyotsna, Umer Farooq, Aroob Fatima, Indrani Kar, Sundal Khuwaja, Unaib Ahmed Memon, Versha Kumari, Piyush Puri, Zaid M Aslam and 6 more

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tamam MohamadCardiology, Wayne State University, Detroit, USA.
Fnu JyotsnaMedicine, Dr. B.R. Ambedkar State Institute of Medical Sciences, Mohali, IND.
Umer FarooqMedicine, CMH (Combined Military Hospital) Lahore Medical College and Institute of Dentistry, Lahore, PAK.
Aroob FatimaMedicine, Ejaz Sikandar Memorial Hospital, Kanganpur, PAK.
Indrani KarMedicine, Lady Hardinge Medical College, New Delhi, IND.
Sundal KhuwajaMedicine, Liaquat University of Medical and Health Sciences, Jamshoro, PAK.
Unaib Ahmed MemonInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, PAK.
Versha KumariMedicine, Liaquat University of Medical and Health Sciences, Jamshoro, PAK.
Piyush PuriMedicine, Adesh Institute of Medical Science and Research, Bathinda, IND.
Zaid M AslamInternal Medicine, Ziauddin University, Karachi, PAK.
Zachary ElderMedical Education, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.
Antonella PaladiniDepartment of MESVA (Life, Health, and Environmental Sciences), University of L'Aquila, L'Aquila, ITA.
Mahima KhatriMedicine and Surgery, Dow University of Health Sciences, Karachi, PAK.
Satesh KumarMedicine and Surgery, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, PAK.
Muhammad Ali MuzammilInternal Medicine, Dow University of Health Sciences, Karachi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of cardiovascular medicine is undergoing a transformative shift towards personalized medicinal therapy, particularly in the context of post stent implantation. This narrative review explores the significance, challenges, and future directions of individualized treatment strategies for patients with coronary stents. The review highlights the pivotal role of personalized approaches in optimizing treatment efficacy and minimizing adverse events. Real-world clinical studies and trials underscore the importance of tailoring antiplatelet therapy based on platelet function testing, genetic testing, and risk scoring. These studies reveal that personalized medicinal treatment improves clinical outcomes by balancing preventing thrombotic events and mitigating bleeding risks. Challenges, including cost, test availability, patient adherence, and ethical considerations, are discussed in depth, shedding light on the complexities of implementing personalized approaches. Technological advancements, including omics data integration, artificial intelligence, and big data analytics, shape the future of personalized medicinal therapy. These tools enable precise pharmacogenomic selection of medications and the development of integrated risk-scoring systems. Patient engagement and education are also central, with empowered patients and remote monitoring contributing to collaborative decision-making. In conclusion, the narrative review underscores that personalized medicinal therapy post stent implantation holds immense promise for revolutionizing cardiovascular care. By embracing a comprehensive approach that considers genetics, clinical factors, and patient preferences, healthcare providers can optimize treatment outcomes and improve patient quality of life. The evolving landscape of personalized medicine offers a glimpse into a future where tailored treatment strategies become the cornerstone of precision cardiovascular care.

Indexed as

bare metal stentscardiovascular medicinecoronary stent implantationdrug-eluting stentsheartimplantationstenttailored treatment strategiestechnological advancementtherapy

Identifiers

PMID37746355
PMCPMC10516147

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.