Evidence mapPaperPMID 37746454Full record

ReviewCureus2023

Exploring the Complex Connection Between Diabetes and Cardiovascular Disease: Analyzing Approaches to Mitigate Cardiovascular Risk in Patients With Diabetes.

Fnu Jyotsna, Areeba Ahmed, Kamal Kumar, Paramjeet Kaur, Mitul Hareshkumar Chaudhary, Sagar Kumar, Ejaz Khan, Bushra Khanam, Syeda Urooba Shah, Giustino Varrassi and 3 more

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fnu JyotsnaMedicine, Dr. B. R. Ambedkar Medical College & Hospital, Mohali, IND.
Areeba AhmedMedicine, Fatima Jinnah Medical University, Lahore, PAK.
Kamal KumarMedicine, Chandka Medical College, Larkana, PAK.
Paramjeet KaurInternal Medicine, Guru Gobind Singh Medical College, Faridkot, IND.
Mitul Hareshkumar ChaudharyMedicine, AMA School of Medicine, Makati, PHL.
Sagar KumarMedicine, Chandka Medical College, Larkana, PAK.
Ejaz KhanDermatology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.
Bushra KhanamInternal Medicine, National Tuberculosis Control Center, Kathmandu, NPL.
Syeda Urooba ShahMedicine, Jinnah Sindh Medical University, Karachi, PAK.
Giustino VarrassiPain Medicine, Paolo Procacci Foundation, Rome, ITA.
Mahima KhatriMedicine and Surgery, Dow University of Health Sciences, Karachi, PAK.
Satesh KumarMedicine and Surgery, Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, PAK.
Kishan Ashokbhai KakadiyaMedicine, Government Medical College, Surat, Surat, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in individuals diagnosed with diabetes mellitus. This narrative review offers a comprehensive examination of the complex correlation between diabetes and cardiovascular complications. The objective of this review is to analyze the most recent evidence on preventive measures and treatment options for mitigating cardiovascular risk in patients with diabetes, by synthesizing existing literature. Insulin resistance plays a crucial role in connecting diabetes and CVD, leading to the development of dyslipidemia and atherogenesis. As a result, the risk of cardiovascular events in individuals with diabetes is significantly elevated. Moreover, the presence of hyperglycemia-induced oxidative stress and inflammation serves to intensify endothelial dysfunction and vascular damage, thereby exacerbating the risk of cardiovascular complications. The interaction between diabetes and CVD frequently speeds up the development of atherosclerotic plaque, making the plaque more prone to rupture. This can lead to severe cardiovascular events such as myocardial infarction and stroke. It is crucial to comprehend the intricate relationship between diabetes and CVD in order to formulate effective strategies aimed at enhancing patient outcomes and mitigating the burden associated with these interconnected chronic conditions. Healthcare practitioners can enhance the quality of life and reduce mortality rates associated with CVD in diabetic patients by thoroughly examining evidence-based preventive measures and treatment options. This approach allows them to make informed decisions when managing cardiovascular risk. In summary, this narrative review provides a valuable resource for healthcare professionals and researchers, presenting a comprehensive analysis of the complex relationship between diabetes and CVD. By providing a comprehensive analysis of the latest evidence and elucidating the underlying mechanisms, this review seeks to establish a foundation for the development of innovative strategies in diabetes management. These strategies have the potential to significantly improve cardiovascular outcomes and enhance overall patient care.

Indexed as

cardiovascular disease (cvd)cardiovascular riskdiabetesinsulin resistancepreventive measurestreatment options

Identifiers

PMID37746454
PMCPMC10511351

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.