Evidence mapPaperPMID 37747553Full record

ReviewArchives of gynecology and obstetrics2024

PCOS and vitamin D: a clinical appraisal.

Radmila Sparic, Mladen Andjic, Daniele Vergara, Andrea Morciano, Ottavia D'Oria, Giorgio Maria Baldini, Antonio Malvasi, Andrea Tinelli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Radmila SparicClinic for Gynecology and Obstetrics, University Clinical Centre of Serbia, 11000, Belgrade, Serbia.ORCID 0000-0003-0515-1951
Mladen AndjicClinic for Gynecology and Obstetrics, University Clinical Centre of Serbia, 11000, Belgrade, Serbia.ORCID 0000-0002-6312-5404
Daniele VergaraDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Strada Prov. le Lecce-Monteroni, 73100, Lecce, Italy.ORCID 0000-0002-2396-7674
Andrea MorcianoDepartment of Gynecology and Obstetrics, Pia Fondazione "Card. G. Panico", Tricase, Lecce, Italy.ORCID 0000-0001-5420-4277
Ottavia D'OriaDepartment of Medical and Surgical Sciences and Translational Medicine, Translational Medicine and Oncology, Rome, Italy.ORCID 0000-0002-3482-1523
Giorgio Maria BaldiniMOMO Ferti LIFE IVF Center, Bisceglie, Italy.ORCID 0000-0002-5061-8007
Antonio MalvasiDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70121, Bari, Italy.ORCID 0000-0001-6940-7608
Andrea TinelliDepartment of Obstetrics and Gynecology and CERICSAL, (CEntro di RIcerca Clinico SALentino), Veris delli Ponti Hospital, Via Giuseppina delli Ponti, 73020, Scorrano, Lecce, Italy. andreatinelli@gmail.com.ORCID 0000-0001-8426-8490
Ospedale degli Infermi · ITOspedale Veris Delli Ponti Scorrano · ITSapienza University of Rome · ITUniversity of Bari Aldo Moro · ITUniversity of Belgrade · RSUniversity of Salento · ITUniverzitetski Klinički Centar Srbije · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePolycystic ovary syndrome (PCOS) is the most common endocrine-reproductive disease linked not just to infertility but also to serious comorbidities. There is a reported association between low vitamin D levels and multiple health conditions including PCOS. This narrative review aims to analyze the role of vitamin D in PCOS development, use of the vitamin D in the treatment of PCOS, and the molecular basis of these observations.

methodsA Medline and PubMed research was performed, during the years 1990-2023, using a combination of keywords on such topic. According to the author's evaluation and target, papers were identified and included for a narrative review.

resultsThere are associations between lower levels of vitamin D and PCOS, as well as with insulin resistance, metabolic syndrome, hyperandrogenemia, metabolic and endocrine disorders as well as the onset of oxidative stress and pro-inflammatory milieu, in PCOS women.

conclusionVitamin D has a role in pathologic changes linked to PCOS. Molecular and clinical investigations which give new information about the role of vitamin D in the development of PCOS and related endocrine and metabolic disturbance are further needed.

Indexed as

Insulin ResistancePolycystic Ovary SyndromeCross-Sectional StudiesFemaleHumansMultimorbidityVitamin DVitaminsVitamin DVitaminsEndocrine disordersInsulin resistanceMetabolic syndromePCOSVitamin D

Identifiers

PMID37747553
OpenAlexW4387002493

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.