Evidence map›Paper›PMID 37749102›Full record

Trial reportScientific reports2023

Impact of on-site pharmacists in residential aged care facilities on the quality of medicines use: a cluster randomised controlled trial (PiRACF study).

Ibrahim Haider, Sam Kosari, Mark Naunton, Theo Niyonsenga, Jane Koerner, Gregory Peterson, Rachel Davey

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ibrahim HaiderDiscipline of Pharmacy, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia. Ibrahim.Haider@canberra.edu.au.
Sam KosariDiscipline of Pharmacy, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
Mark NauntonDiscipline of Pharmacy, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
Theo NiyonsengaHealth Research Institute, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
Jane KoernerHealth Research Institute, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
Gregory PetersonSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS, 7005, Australia.
Rachel DaveyHealth Research Institute, Faculty of Health, University of Canberra, Bruce, ACT, 2617, Australia.
University of Canberra · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residents of residential aged care facilities (RACFs) have a high prevalence of use of potentially inappropriate medications (PIMs) and resultant medicines-related harm. This study investigated the effect of an on-site pharmacist model on PIMs use and other medication outcomes for residents in RACFs. A multi-facility, non-blind, cluster randomised controlled trial, with randomisation at the facility level, was conducted. Fifteen facilities enrolled and participated in the study, 7 facilities (560 residents) were allocated to the intervention arm and 8 facilities (737 residents) were allocated to the control arm. Each facility in the intervention arm employed an on-site pharmacist for 12 months to perform medication management activities as part of an interdisciplinary care team. The primary outcome was the proportion of residents taking at least one PIM according to the 2019 Beers® Criteria. Using generalised linear mixed-effects models, accounting for confounders and clustering, there was a significant reduction in the proportion of residents prescribed at least one PIM (odds ratio 0.50, 95% confidence interval, 0.335-0.750; p = 0.001) in the intervention arm. There were also significant decreases in the Anticholinergic Cognitive Burden scale and chlorpromazine equivalent daily dose of antipsychotics. The on-site pharmacist intervention significantly improved the appropriateness of medicines use in RACFs.

Indexed as

Antipsychotic AgentsPharmacistsAgedBeerChlorpromazineCluster AnalysisHumansAntipsychotic AgentsChlorpromazine

Identifiers

PMID37749102
PMCPMC10519995
OpenAlexW4387019410

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.