Evidence map›Paper›PMID 37749124›Full record

ArticleScientific reports2023

Influence of electric potential-induced by atmospheric pressure plasma on cell response.

Takamasa Okumura, Chia-Hsing Chang, Kazunori Koga, Masaharu Shiratani, Takehiko Sato

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Takamasa OkumuraFaculty of Information Science and Electrical Engineering, Kyushu University, Fukuoka, Fukuoka, 819-0395, Japan. t.okumura@plasma.ed.kyushu-u.ac.jp.
Chia-Hsing ChangInstitute of Fluid Science, Tohoku University, Sendai, Miyagi, 980-8577, Japan.
Kazunori KogaFaculty of Information Science and Electrical Engineering, Kyushu University, Fukuoka, Fukuoka, 819-0395, Japan.
Masaharu ShirataniFaculty of Information Science and Electrical Engineering, Kyushu University, Fukuoka, Fukuoka, 819-0395, Japan.
Takehiko SatoInstitute of Fluid Science, Tohoku University, Sendai, Miyagi, 980-8577, Japan. takehiko.sato.d7@tohoku.ac.jp.
Kyushu University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma irradiation leads not only active species, but also reactive chemical species, ultraviolet light, electric fields, magnetic fields, and shock waves. To date the effects of reactive chemical species have been mainly discussed. To understand the biological effect caused by an electric potential induced with an atmospheric-pressure plasma, the behavior of cell stimulated by electric potential was investigated using HeLa cell. The cell concentration assay revealed that less than 20% of cells inactivated by potential stimulation and the remained cells proliferate afterward. Fluorescent microscopic observation revealed that potential stimulation is appreciable to transport the molecules through membrane. These results show that potential stimulation induces intracellular and extracellular molecular transport, while the stimulation has a low lethal effect. A possible mechanism for this molecular transport by potential stimulation was also shown using numerical simulation based on an equivalent circuit of the experimental system including adhered HeLa cell. The potential formation caused by plasma generation is decisive in the contribution of plasma science to molecular biology and the elucidation of the mechanism underlying a biological response induction by plasma irradiation.

Indexed as

Atmospheric PressurePlasma GasesHeLa CellsHumansPlasma Gases

Identifiers

PMID37749124
PMCPMC10520067
OpenAlexW4387019365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.