Evidence map›Paper›PMID 37755996›Full record

ReviewToxins2023

New Strategies for Biocontrol of Bacterial Toxins and Virulence: Focusing on Quorum-Sensing Interference and Biofilm Inhibition.

Hua Zhang, Zhen Zhang, Jing Li, Guangyong Qin

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Prevention and Treatment ofPathogens (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
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  12. Article
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  15. Article
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  17. Article
  18. Article
  19. Review
  20. Pathogenic Biofilm Removal Potential of Wild-TypePathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hua ZhangHenan Key Laboratory of Ion Beam Bio-Engineering, College of Physics, Zhengzhou University, Zhengzhou 450000, China.
Zhen ZhangSchool of Food and Biological Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Jing LiSchool of Food and Biological Engineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.
Guangyong QinSchool of Agricultural Sciences, Zhengzhou University, Zhengzhou 450000, China.
Henan University of Economic and Law · CNZhengzhou University · CN

Funding

National Natural Science Foundation of China No. 31802111
6 · The paper itself

Abstract

The overuse of antibiotics and the emergence of multiple-antibiotic-resistant pathogens are becoming a serious threat to health security and the economy. Reducing antimicrobial resistance requires replacing antibiotic consumption with more biocontrol strategies to improve the immunity of animals and humans. Probiotics and medicinal plants have been used as alternative treatments or preventative therapies for a variety of diseases caused by bacterial infections. Therefore, we reviewed some of the anti-virulence and bacterial toxin-inhibiting strategies that are currently being developed; this review covers strategies focused on quenching pathogen quorum sensing (QS) systems, the disruption of biofilm formation and bacterial toxin neutralization. It highlights the probable mechanism of action for probiotics and medicinal plants. Although further research is needed before a definitive statement can be made on the efficacy of any of these interventions, the current literature offers new hope and a new tool in the arsenal in the fight against bacterial virulence factors and bacterial toxins.

Indexed as

BacteriaBacterial ToxinsBiofilmsQuorum SensingAnimalsAnti-Bacterial AgentsHumansProbioticsVirulenceVirulence FactorsAnti-Bacterial AgentsBacterial ToxinsVirulence Factorsbacterial toxinsbiocontrolmedicinal plantsprobioticsvirulence

Identifiers

PMID37755996
PMCPMC10536320
OpenAlexW4386837916

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.