Evidence map›Paper›PMID 37759448›Full record

ArticleCells2023

Orai3 Calcium Channel Contributes to Oral/Oropharyngeal Cancer Stemness through the Elevation of ID1 Expression.

Anthony Nguyen, Youngjae Sung, Sung Hee Lee, Charlotte Ellen Martin, Sonal Srikanth, Wei Chen, Mo K Kang, Reuben H Kim, No-Hee Park, Yousang Gwack and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Calcium channels as pharmacological targets for cancer therapy.Clinical and experimental medicine · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anthony NguyenThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Youngjae SungThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Sung Hee LeeThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Charlotte Ellen MartinThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Sonal SrikanthDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Wei ChenThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Mo K KangThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Reuben H KimThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
No-Hee ParkThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
Yousang GwackDepartment of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0002-2821-9245
Yong KimUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA.ORCID 0000-0002-6220-4063
Ki-Hyuk ShinThe Shapiro Family Laboratory of Viral Oncology and Aging Research, UCLA School of Dentistry, Los Angeles, CA 90095, USA.
University of California, Los Angeles · USUCLA Jonsson Comprehensive Cancer Center

Funding

Targeting Grainyhead-Like 2 Suppresses Entry Factors of SARS-CoV-2 in Epithelial Cells of Oral Mucosa.R21DE031074 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHEN, WEI · 2022 to 2023
$429k
NIDCR NIH HHS R21 DE031074
6 · The paper itself

Abstract

Emerging evidence indicates that intracellular calcium (Ca

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsOropharyngeal NeoplasmsCalcium ChannelsHumansHyperplasiaInhibitor of Differentiation Protein 1Squamous Cell Carcinoma of Head and NeckCalcium ChannelsID1 protein, humanInhibitor of Differentiation Protein 1Orai3 protein, humancalciumcancer stem-like cellsID1Orai3OSCC

Identifiers

PMID37759448
PMCPMC10527097
OpenAlexW4386525395

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.