Evidence map›Paper›PMID 37759508›Full record

ArticleCells2023

Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer.

Sho Shiino, Momoko Tokura, Jun Nakayama, Masayuki Yoshida, Akihiko Suto, Yusuke Yamamoto

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sho ShiinoDepartment of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Momoko TokuraLaboratory of Integrative Oncology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Jun NakayamaLaboratory of Integrative Oncology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.
Masayuki YoshidaDepartment of Diagnostic Pathology, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Akihiko SutoDepartment of Breast Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.ORCID 0000-0003-1458-2593
Yusuke YamamotoLaboratory of Integrative Oncology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.ORCID 0000-0002-5262-8479
Tokyo National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human epidermal growth factor receptor 2 (HER2) protein, which is characterized by the amplification of

Indexed as

Breast NeoplasmsBase SequenceFemaleHumansSequence Analysis, RNASingle-Cell AnalysisStaining and Labelingbreast cancerheterogeneityhuman epidermal growth factor receptor 2

Identifiers

PMID37759508
PMCPMC10527746
OpenAlexW4386780332

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.