Evidence map›Paper›PMID 37759824›Full record

ArticleBiomolecules2023

Metabolomics Analysis and Biochemical Profiling of Arsenic-Induced Metabolic Impairment and Disease Susceptibility.

Syed Muhammad Shoaib, Samina Afzal, Ali Feezan, Muhammad Sajid Hamid Akash, Ahmed Nadeem, Tahir Maqbool Mir

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Syed Muhammad ShoaibDepartment of Pharmaceutical Chemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.ORCID 0009-0004-6796-9729
Samina AfzalDepartment of Pharmaceutical Chemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Ali FeezanDepartment of Pharmaceutical Chemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Muhammad Sajid Hamid AkashDepartment of Pharmaceutical Chemistry, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0002-9446-5233
Ahmed NadeemDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-2038-8367
Tahir Maqbool MirNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, Oxford, MS 38677, USA.ORCID 0000-0002-7294-3660
Bahauddin Zakariya University · PKGovernment College University, Faisalabad · PKKing Saud University · SAUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to conduct a comprehensive biochemical profiling and metabolomics analysis to investigate the effects of arsenic-induced metabolic disorders, with a specific focus on disruptions in lipid metabolism, amino acid metabolism, and carbohydrate metabolism. Additionally, we sought to assess the therapeutic potential of resveratrol (RSV) as a remedy for arsenic-induced diabetes, using metformin (MF) as a standard drug for comparison. We measured the total arsenic content in mouse serum by employing inductively coupled plasma mass spectrometry (ICP-MS) after administering a 50-ppm solution of sodium arsenate (50 mg/L) in purified water. Our findings revealed a substantial increase in total arsenic content in the exposed group, with a mean value of 166.80 ± 8.52 ppb (

Indexed as

Antifibrinolytic AgentsArsenicAmino AcidsAnimalsCarnitineCarnitine O-PalmitoyltransferaseDisease SusceptibilityGlucose-6-PhosphataseMiceAmino AcidsAntifibrinolytic AgentsArsenicCarnitineCarnitine O-PalmitoyltransferaseGlucose-6-Phosphataseamino acid metabolomesarsenic metabolitesICP-MSlipid metabolomestandem mass spectrophotometer (MS/MS)

Identifiers

PMID37759824
PMCPMC10526798
OpenAlexW4386929956

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.