Evidence map›Paper›PMID 37763334›Full record

ReviewLife (Basel, Switzerland)2023

Regulatory T Cells in Atherosclerosis: Is Adoptive Cell Therapy Possible?

Alexey V Churov, Yegor S Chegodaev, Victoria A Khotina, Vladimir P Ofitserov, Alexander N Orekhov

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. The role of immune cells in different stages of atherosclerosis.International journal of medical sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alexey V ChurovInstitute on Aging Research, Russian Gerontology Clinical Research Center, Pirogov Russian National Research Medical University, 129226 Moscow, Russia.ORCID 0000-0002-3920-7581
Yegor S ChegodaevInstitute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, 125315 Moscow, Russia.
Victoria A KhotinaInstitute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, 125315 Moscow, Russia.ORCID 0000-0003-2096-3237
Vladimir P OfitserovMoscow Aviation Institute, National Research University, 4 Volokolamskoe Shosse, 125993 Moscow, Russia.ORCID 0000-0002-8055-3785
Alexander N OrekhovInstitute of General Pathology and Pathophysiology, 8 Baltiiskaya Street, 125315 Moscow, Russia.ORCID 0000-0002-3318-4681
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RUMoscow Aviation Institute · RUPirogov Russian National Research Medical University · RU

Funding

Russian Science Foundation 22-25-00650
6 · The paper itself

Abstract

Atherosclerosis is an insidious vascular disease with an asymptomatic debut and development over decades. The aetiology and pathogenesis of atherosclerosis are not completely clear. However, chronic inflammation and autoimmune reactions play a significant role in the natural course of atherosclerosis. The pathogenesis of atherosclerosis involves damage to the intima, immune cell recruitment and infiltration of cells such as monocytes/macrophages, neutrophils, and lymphocytes into the inner layer of vessel walls, and the accumulation of lipids, leading to vascular inflammation. The recruited immune cells mainly have a pro-atherogenic effect, whereas CD4

Indexed as

atherosclerosisCAR TregFOXP3inflammationregulatory T cells

Identifiers

PMID37763334
PMCPMC10532736
OpenAlexW4386850175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.