Evidence map›Paper›PMID 37764214›Full record

ArticleMolecules (Basel, Switzerland)2023

Analyzing the Material Basis of Anti-RSV Efficacy of Lonicerae japonicae Flos Based on the PK-PD Model.

Yuting Liang, Mingjun Liu, Yanghai Wang, Lu Liu, Yan Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuting LiangInstitute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Mingjun LiuInstitute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yanghai WangInstitute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Lu LiuInstitute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Yan GaoInstitute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shandong University of Traditional Chinese Medicine · CN

Funding

Department of Science and Technology of Shandong Province 2021CXGC010511
6 · The paper itself

Abstract

Lonicerae japonicae Flos (LJF) possesses a good anti-respiratory syncytial virus (RSV) effect. However, the material basis of LJF in treating RSV is still unclear. In this study, a sensitive and accurate quantitative method based on UHPLC-QQQ MS was established and validated for the simultaneous determination of the 15 ingredients from LJF in RSV-infected mice plasma. Multiple reaction monitoring was performed for quantification of the standards and of the internal standard in plasma. All the calibration curves show good linear regression within the linear range (r

Indexed as

Antiviral AgentsDrugs, Chinese HerbalLoniceraPlant ExtractsRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsAnimalsChromatography, High Pressure LiquidMiceAntiviral AgentsDrugs, Chinese Herballonicerae flosPlant Extractseffective ingredientLonicerae japonicae FlosPK-PD modelrespiratory syncytial virusUPLC-MS/MS

Identifiers

PMID37764214
PMCPMC10537356
OpenAlexW4386444514

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.