Evidence map›Paper›PMID 37764474›Full record

ArticleMolecules (Basel, Switzerland)2023

Stereospecificity of Ginsenoside AD-1 and AD-2 Showed Anticancer Activity via Inducing Mitochondrial Dysfunction and Reactive Oxygen Species Mediate Cell Apoptosis.

Xude Wang, Meng Ding, Hong Zhao, Mengru Zhou, Xuan Lu, Yuanyuan Sun, Qinggao Zhang, Yuqing Zhao, Ruoyu Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Xude WangDepartment of Oncology, The Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Meng DingCollege of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou 061000, China.
Hong ZhaoChina College of Life and Health, Dalian University, Dalian 116622, China.
Mengru ZhouChronic Disease Research Center, Medical College, Dalian University, Dalian 116622, China.
Xuan LuChina College of Life and Health, Dalian University, Dalian 116622, China.
Yuanyuan SunSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Qinggao ZhangKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji 133002, China.
Yuqing ZhaoSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Ruoyu WangDepartment of Oncology, The Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China.
Dalian Medical University · CNDalian University · CNShenyang Pharmaceutical University · CNAffiliated Zhongshan Hospital of Dalian University · CNCangzhou Normal University · CNYanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, the anti-cancer activity and molecular mechanisms of the isomers of AD-1 and AD-2 (20(

Indexed as

Antineoplastic AgentsApoptosisGinsenosidesMitochondriaReactive Oxygen SpeciesCell Line, TumorCell ProliferationGlycolysisHumansPhosphorylationStereoisomerismAntineoplastic AgentsGinsenosidesReactive Oxygen SpeciesAD-1 and AD-2anti-cancerapoptosisisomersROS

Identifiers

PMID37764474
PMCPMC10536438
OpenAlexW4386895520

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.