Evidence map›Paper›PMID 37764665›Full record

ReviewNutrients2023

The Commonly Used Stabilizers for Phytochemical-Based Nanoparticles: Stabilization Effects, Mechanisms, and Applications.

Fang Zhou, Tiffany Peterson, Zhaoyang Fan, Shu Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fang ZhouCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.ORCID 0000-0002-1982-2982
Tiffany PetersonCollege of Integrative Sciences and Arts, Arizona State University, Phoenix, AZ 85004, USA.
Zhaoyang FanSchool of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85281, USA.ORCID 0000-0002-6185-2325
Shu WangCollege of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.ORCID 0000-0001-8078-9942

Funding

NCCIH NIH HHS 1R15AT010395NCCIH NIH HHS R15 AT010395
6 · The paper itself

Abstract

Phytochemicals, such as resveratrol, curcumin, and quercetin, have many benefits for health, but most of them have a low bioavailability due to their poor water solubility and stability, quick metabolism, and clearance, which restricts the scope of their potential applications. To overcome these issues, different types of nanoparticles (NPs), especially biocompatible and biodegradable NPs, have been developed. NPs can carry phytochemicals and increase their solubility, stability, target specificity, and oral bioavailability. However, NPs are prone to irreversible aggregation, which leads to NP instability and loss of functions. To remedy this shortcoming, stabilizers like polymers and surfactants are incorporated on NPs. Stabilizers not only increase the stability of NPs, but also improve their characteristics. The current review focused on discussing the state of the art in research on synthesizing phytochemical-based NPs and their commonly employed stabilizers. Furthermore, stabilizers in these NPs were also discussed in terms of their applications, effects, and underlying mechanisms. This review aimed to provide more references for developing stabilizers and NPs for future research.

Indexed as

CurcuminNanoparticlesPhytochemicalsResveratrolSolubilityCurcuminPhytochemicalsResveratrolapplicationmechanismnanoparticlesstabilitystabilizers

Identifiers

PMID37764665
PMCPMC10534333

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.