Evidence map›Paper›PMID 37765268›Full record

ArticlePharmaceutics2023

Polymorphism and Multi-Component Crystal Formation of GABA and Gabapentin.

Daniel Komisarek, Fulya Demirbas, Takin Haj Hassani Sohi, Klaus Merz, Carsten Schauerte, Vera Vasylyeva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniel KomisarekLaboratory for Crystal Engineering, Department of Inorganic and Structural Chemistry 1, Heinrich-Heine-University Dueseldorf, Universitaetsstraße 1, 40225 Duesseldorf, Germany.
Fulya DemirbasLaboratory for Crystal Engineering, Department of Inorganic and Structural Chemistry 1, Heinrich-Heine-University Dueseldorf, Universitaetsstraße 1, 40225 Duesseldorf, Germany.
Takin Haj Hassani SohiLaboratory for Crystal Engineering, Department of Inorganic and Structural Chemistry 1, Heinrich-Heine-University Dueseldorf, Universitaetsstraße 1, 40225 Duesseldorf, Germany.ORCID 0000-0001-6902-077X
Klaus MerzInorganic Chemistry 1, Ruhr-University Bochum, Universitaetstrasse 150, 44801 Bochum, Germany.
Carsten SchauerteSOLID-CHEM GmbH, Universitaetstrasse 136, 44799 Bochum, Germany.
Vera VasylyevaLaboratory for Crystal Engineering, Department of Inorganic and Structural Chemistry 1, Heinrich-Heine-University Dueseldorf, Universitaetsstraße 1, 40225 Duesseldorf, Germany.ORCID 0000-0001-7734-7406
Heinrich Heine University Düsseldorf · DERuhr University Bochum · DE

Funding

Deutsche Forschungsgemeinschaft 440366605
6 · The paper itself

Abstract

This study exploits the polymorphism and multi-component crystal formation of γ-amino butanoic acid (GABA) and its pharmaceutically active derivative, gabapentin. Two polymorphs of GABA and both polymorphs of gabapentin are structurally revisited, together with gabapentin monohydrate. Hereby, GABA form

Indexed as

APIcrystallizationGABAgabapentinhydrogen bondmulticomponent crystalsnon-covalent interactionspharmaceutical crystal engineeringpolymorphism

Identifiers

PMID37765268
PMCPMC10536459
OpenAlexW4386602376

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.