Evidence map›Paper›PMID 37767034›Full record

ArticleNanoscale advances2023

Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer.

Mouna Selmi, Abir Salek, Mahassen Barboura, Leila Njim, Amine Trabelsi, Aida Lahmar, Nolwenn Lautram, Emilie Roger, Tarek Baati, Leila Chekir Ghedira

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Mouna SelmiLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
Abir SalekLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
Mahassen BarbouraLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
Leila NjimService d'Anatomie Pathologique, CHU de Monastir, Université de Monastir Tunisia.
Amine TrabelsiLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
Aida LahmarLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
Nolwenn LautramUniversité d'Angers, INSERM, CNRS, MINT, SFR-ICAT F-49000 Angers France.
Emilie RogerUniversité d'Angers, INSERM, CNRS, MINT, SFR-ICAT F-49000 Angers France.
Tarek BaatiLaboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique, Biotechpôle Sidi Thabet 2020 Tunisia tarek.baati@gmail.com +216 71 537 688 +216 71 537 666.ORCID https://orcid.org/0000-0002-6603-5615
Leila Chekir GhediraLaboratoire des Substances Naturelles Bioactives et Biotechnologie UR17ES49, Faculté de Médecine Dentaire, Université de Monastir Tunisia.
University of Monastir · TNCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the third most common worldwide. Depending on its stage, chemotherapy is usually given after surgery when CRC has already metastasized to other organs like the liver or lungs. Unfortunately, the current antineoplastics used for CRC therapies involve toxicity and side effects due to their lack of site-specificity. To overcome the drawbacks of heavy chemotherapy, this study proposes to assess the efficacy of thymoquinone (TQ), a bioactive constituent of black seeds (

Identifiers

PMID37767034
PMCPMC10521245
OpenAlexW4386077660

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.