Evidence map›Paper›PMID 37772128›Full record

ReviewRegenerative therapy2023

Emerging advances in hydrogel-based therapeutic strategies for tissue regeneration.

Wenqi Li, Jing Hu, Cheng Chen, Xinyue Li, Honghua Zhang, Yanru Xin, Qingchang Tian, Shuling Wang

Open access · goldAbstract readReview
In one paragraph

Review in Regenerative therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenqi LiSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Jing HuSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Cheng ChenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Xinyue LiSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Honghua ZhangSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Yanru XinSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Qingchang TianSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Shuling WangSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
Hangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant developments in cell therapy and biomaterial science have broadened the therapeutic landscape of tissue regeneration. Tissue damage is a complex biological process in which different types of cells play a specific role in repairing damaged tissues and growth factors strictly regulate the activity of these cells. Hydrogels have become promising biomaterials for tissue regeneration if appropriate materials are selected and the hydrogel properties are well-regulated. Importantly, they can be used as carriers for living cells and growth factors due to the high water-holding capacity, high permeability, and good biocompatibility of hydrogels. Cell-loaded hydrogels can play an essential role in treating damaged tissues and open new avenues for cell therapy. There is ample evidence substantiating the ability of hydrogels to facilitate the delivery of cells (stem cell, macrophage, chondrocyte, and osteoblast) and growth factors (bone morphogenetic protein, transforming growth factor, vascular endothelial growth factor and fibroblast growth factor). This paper reviewed the latest advances in hydrogels loaded with cells or growth factors to promote the reconstruction of tissues. Furthermore, we discussed the shortcomings of the application of hydrogels in tissue engineering to promote their further development.

Indexed as

3D-bioprintingCells therapiesGrowth factorsHydrogelTissue engineering

Identifiers

PMID37772128
PMCPMC10523184
OpenAlexW4386880804

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.