Evidence map›Paper›PMID 37776177›Full record

ArticleJournal of neurotrauma2024

Characterization of Vasogenic and Cytotoxic Brain Edema Formation After Experimental Traumatic Brain Injury by Free Water Diffusion Magnetic Resonance Imaging.

Senbin Hu, Carina Exner, Rebecca Isabella Sienel, Antonia Clarissa When, Fatma Burcu Seker, Fanni Magdane Boldoczki, Yinghuimin Guo, Marco Duering, Ofer Pasternak, Nikolaus Plesnila and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  5. Diffuse traumatic brain injury in mice is associated with a transient mismatch of cerebral blood flow and energy metabolism.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Senbin HuInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Carina ExnerInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Rebecca Isabella SienelInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Antonia Clarissa WhenInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Fatma Burcu SekerInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Fanni Magdane BoldoczkiInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Yinghuimin GuoInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Marco DueringMedical Image Analysis Center (MIAC) and Department of Biomedical Engineering, University of Basel, Basel, Switzerland.
Ofer PasternakNeuroscience Image Computing, Harvard Medical School, Boston, Massachusetts, USA.
Nikolaus PlesnilaInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Susanne M SchwarzmaierInstitute for Stroke and Dementia Research (ISD)and Ludwig-Maximilians University (LMU), Munich, Germany.
Munich Cluster for Systems Neurology · DELudwig-Maximilians-Universität München · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain edema formation is a key factor for secondary tissue damage after traumatic brain injury (TBI), however, the type of brain edema and the temporal profile of edema formation are still unclear. We performed free water imaging, a bi-tensor model based diffusion MRI analysis, to characterize vasogenic brain edema (VBE) and cytotoxic edema (CBE) formation up to 7 days after experimental TBI. Male C57/Bl6 mice were subjected to controlled cortical impact (CCI) or sham surgery and investigated by MRI 4h, 1, 2, 3, 5, and 7 days thereafter (

Indexed as

Brain EdemaBrain Injuries, TraumaticContusionsAnimalsDiffusion Magnetic Resonance ImagingEdemaHumansMagnetic Resonance ImagingMaleMiceWaterWatercytotoxic brain edemademyelinizationdiffusion-weighted MRIfree-water imagingtraumatic brain injuryvasogenic brain edema

Identifiers

PMID37776177
PMCPMC10908318
OpenAlexW4387210085

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.