Evidence map›Paper›PMID 37776543›Full record

ArticleAge and ageing2023

Call to action: a five nations consensus on the use of intravenous zoledronate after hip fracture.

Antony Johansen, Opinder Sahota, Frances Dockery, Alison J Black, Alasdair M J MacLullich, M Kassim Javaid, Emer Ahern, Celia L Gregson

Erratum issuedOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
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  6. Mental disorders and osteoporosis treatment in patients with hip fracture-a Danish population-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  7. Article
  8. High fracture risk, limited evidence: rethinking osteoporosis treatment in chronic kidney disease.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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  14. Pre-fracture functional status and 30-day recovery predict 5-year survival in patients with hip fracture: findings from a prospective real-world study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Observational
  15. Article
  16. Assessing the impact of the 5 Nations Consensus Paper on IV Zolendronate administration post-hip fracture in older patients: experience from a UK teaching hospital.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 2 countries.

Antony JohansenUniversity Hospital of Wales and College of Medicine, Cardiff University, Cardiff CF14 4XW, UK.
Opinder SahotaDepartment of Health Care of Older People, Nottingham University Hospital, Nottingham NG7 2UH, UK.
Frances DockeryBeaumont Hospital, Dublin 9, Ireland.
Alison J BlackNHS Grampian, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK.
Alasdair M J MacLullichAgeing and Health Research Group, University of Edinburgh, Edinburgh EH9 3EG, UK.ORCID 0000-0003-3159-9370
M Kassim JavaidFalls and Fragility Fracture Audit Programme, Royal College of Physicians, London NW1 4LE, UK.
Emer AhernCork University Hospital and University College Cork, Cork, Ireland.
Celia L GregsonMusculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol BS10 5NB, UK.
Aberdeen Royal Infirmary · GBBeaumont Hospital · IENuffield Orthopaedic Centre · GBRoyal United Hospital · GBUniversity College Cork · IEUniversity Hospital of Wales · GBUniversity of Edinburgh · GBUniversity of Nottingham · GB

Funding

Versus Arthritis 22086
6 · The paper itself

Abstract

Currently in the UK and Ireland, after a hip fracture most patients do not receive bone protection medication to reduce the risk of refracture. Yet randomised controlled trial data specifically examining patients with hip fracture have shown that intravenous zoledronate reduces refracture risk by a third. Despite this evidence, use of intravenous zoledronate is highly variable following a hip fracture; many hospitals are providing this treatment, whilst most are currently not. A range of clinical uncertainties, doubts over the evidence base and practical concerns are cited as reasons. This paper discusses these concerns and provides guidance from expert consensus, aiming to assist orthogeriatricians, pharmacists and health services managers establish local protocols to deliver this highly clinically and cost-effective treatment to patients before they leave hospital, in order to reduce costly re-fractures in this frail population.

Indexed as

Bone Density Conservation AgentsHip FracturesOsteoporotic FracturesZoledronic AcidHumansIrelandBone Density Conservation AgentsZoledronic Acidhip fractureolder peopleosteoporosissecondary preventionzoledronate

Identifiers

PMID37776543
PMCPMC10542103
OpenAlexW4387215181

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.