ArticleClinical kidney journal2023
The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes.
Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 14 citations in OpenAlex.
- Comparison of adverse renal events between ranibizumab and aflibercept in patients with diabetic macular oedema: A global network study.Eye (London, England) · 2026Article
- Association analysis of PTPN1 gene SNP with retinopathy and nephropathy in type 2 diabetes mellitus and development of predictive line graph in Chinese population.Scientific reports · 2026Article
- Retinal Ischemic Perivascular Lesions are Associated with Multifactorial Disease Burden and Severity of Diabetic Retinopathy.Ophthalmology science · 2026Article
- Diabetic retinopathy Is associated with histologic severity of diabetic kidney disease and systemic inflammation.Acta diabetologica · 2026Article
- Albuminuria, but not eGFR, tracks diabetic retinopathy severity and retinal ischemia: population-based discovery, clinical replication, and OCTA evidence.Frontiers in endocrinology · 2026Article
- Diabetic retinopathy severity is associated with renal function deterioration in patients with diabetic kidney disease: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Prediction of advanced chronic kidney disease through retinal fundus images by deep learning.Scientific reports · 2025Article
- Hypertensive Nephrosclerosis: Pathological Changes and Overlap with Diabetic Nephropathy.Cureus · 2025Review
- Development and validation of a model that predicts the risk of diabetic kidney disease in type 2 diabetes mellitus patients: a retrospective study.Frontiers in endocrinology · 2025Article
- The influence of renal function on surgical outcomes of vitrectomy in patients with proliferative diabetic retinopathy.Frontiers in endocrinology · 2025Article
- Nomenclature of renal involvement in diabetes mellitus: unify to manage diversity.Frontiers in medicine · 2025Review
- Tonabersat suppresses priming/activation of the NOD-like receptor protein-3 (NLRP3) inflammasome and decreases renal tubular epithelial-to-macrophage crosstalk in a model of diabetic kidney disease.Cell communication and signaling : CCS · 2024Article
- Shared signaling pathways and comprehensive therapeutic approaches among diabetes complications.Frontiers in medicine · 2024Review
- Evaluating the potential of retinal photography in chronic kidney disease detection: a review.PeerJ · 2024Review
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Authors and funding
36 authors at 19 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Up to 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD) on kidney biopsy. Diabetic retinopathy (DR) is a microvascular complication of diabetes frequently associated with diabetic nephropathy (DN). The objective of the current study was to investigate the kidney outcomes and survival in patients with biopsy diagnoses of DN and NDKD according to the presence of DR. Methods: We conducted an observational, multicentre and retrospective study of the pathological findings of renal biopsies from 832 consecutive patients with diabetes from 2002 to 2014 from 18 nephrology departments. The association of DR with kidney replacement therapy (KRT) or survival was assessed by Kaplan-Meier and Cox regression analyses. Results: Of 832 patients with diabetes and renal biopsy, 768 had a retinal examination and 221/768 (22.6%) had DR. During a follow-up of 10 years, 288/760 (37.9%) patients with follow-up data needed KRT and 157/760 (20.7%) died. The incidence of KRT was higher among patients with DN (alone or with NDKD) and DR [103/175 (58.9%)] than among patients without DR [88/216 (40.7%), Conclusions: DR is associated with a higher risk of progression to kidney failure in patients with histological DN and in patients with NDKD.
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