Evidence map›Paper›PMID 37781225›Full record

ArticleFrontiers in physiology2023

p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle.

Jaspreet Kalra, Mykhaylo Artamonov, Hua Wang, Aaron Franke, Zaneta Markowska, Li Jin, Zygmunt S Derewenda, Ramon J Ayon, Avril Somlyo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jaspreet KalraDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Mykhaylo ArtamonovDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Hua WangDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Aaron FrankeDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Zaneta MarkowskaDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Li JinDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Zygmunt S DerewendaDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Ramon J Ayon *Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
Avril Somlyo *Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA, United States.
University of Virginia · USMartha Jefferson Hospital · USNational Institutes of Health · US

Funding

New Signaling Networks in Vascular Smooth MuscleR01HL147555 · NHLBI · UNIVERSITY OF VIRGINIA · PI DEREWENDA, ZYGMUNT S, SOMLYO, AVRIL V. · 2020 to 2024
$3.6M
RhoA Signaling and StrokeR21NS118647 · NINDS · UNIVERSITY OF VIRGINIA · PI DEREWENDA, ZYGMUNT S, SOMLYO, AVRIL V. · 2020 to 2020
$439k
NHLBI NIH HHS R01 HL147555NINDS NIH HHS R21 NS118647
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MLCKmylk1p90 ribosomal S6 kinasePDK1Pyk2RSK2smooth muscle

Identifiers

PMID37781225
PMCPMC10533999
OpenAlexW4386698384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.