Evidence map›Paper›PMID 37781401›Full record

ReviewFrontiers in immunology2023

Fat and inflammation: adipocyte-myeloid cell crosstalk in atherosclerosis.

Aleksandra M Mazitova, Ana Cristina Márquez-Sánchez, Ekaterina K Koltsova

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aleksandra M MazitovaCedars-Sinai Cancer, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Ana Cristina Márquez-SánchezCedars-Sinai Cancer, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Ekaterina K KoltsovaCedars-Sinai Cancer, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Cedars-Sinai Medical Center · US

Funding

IL-27R signaling as a negative regulator of innate and adaptive anti-cancer immunity in hepatocellular carcinomaR01CA273925 · NCI · CEDARS-SINAI MEDICAL CENTER · PI KOLTSOVA, EKATERINA · 2022 to 2025
$3.3M
Cytokine mediated regulation of stress myelopoiesis in abdominal aortic aneurysmR01HL149946 · NHLBI · RESEARCH INST OF FOX CHASE CAN CTR · PI KOLTSOVA, EKATERINA · 2020 to 2023
$2.1M
NCI NIH HHS R01 CA273925NHLBI NIH HHS R01 HL149946
6 · The paper itself

Abstract

Adipose tissue inflammation has been implicated in various chronic inflammatory diseases and cancer. Perivascular adipose tissue (PVAT) surrounds the aorta as an extra layer and was suggested to contribute to atherosclerosis development. PVAT regulates the function of endothelial and vascular smooth muscle cells in the aorta and represent a reservoir for various immune cells which may participate in aortic inflammation. Recent studies demonstrate that adipocytes also express various cytokine receptors and, therefore, may directly respond to inflammatory stimuli. Here we will summarize current knowledge on immune mechanisms regulating adipocyte activation and the crosstalk between myeloid cells and adipocytes in pathogenesis of atherosclerosis.

Indexed as

Adipose TissueAtherosclerosisAdipocytesHumansInflammationMyeloid Cellsadipocytesatherosclerosiscytokinesinflammationperivascular adipose tissue

Identifiers

PMID37781401
PMCPMC10540690
OpenAlexW4386837525

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.