Evidence map›Paper›PMID 37790939›Full record

ArticleFrontiers in immunology2023

Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis.

Xuan Wang, Mara Lennard Richard, Tomika S Caldwell, Kamala Sundararaj, Shuzo Sato, Tamara K Nowling, Xian K Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Xuan WangDepartment of General Practice, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Mara Lennard RichardDepartment of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Tomika S CaldwellDepartment of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Kamala SundararajDepartment of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Shuzo SatoDepartment of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Tamara K NowlingDepartment of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Xian K ZhangDepartment of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Medical University of South Carolina · USCentral South University · CNFukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor Fli-1, a member of the ETS family of transcription factors, is implicated in the pathogenesis of lupus disease. Reduced Fli-1 expression in lupus mice leads to decreased renal

Indexed as

Endothelial CellsProto-Oncogene Protein c-fli-1AnimalsChemokine CXCL10HumansKidneyMiceMice, Inbred MRL lprReceptors, CXCR3Chemokine CXCL10CXCL10 protein, humanCXCR3 protein, humanFLI1 protein, humanFli1 protein, mouseProto-Oncogene Protein c-fli-1Receptors, CXCR3chemokineCXCL10CXCR3friend leukemia virus integration 1 transcription factorinflammationlupus nephritis

Identifiers

PMID37790939
PMCPMC10543418
OpenAlexW4386774250

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.