Evidence map›Paper›PMID 37796354›Full record

ArticleApoptosis : an international journal on programmed cell death2024

Different bacterial cargo in apoptotic cells drive distinct macrophage phenotypes.

Ana Carolina Guerta Salina, Letícia de Aquino Penteado, Naiara Naiana Dejani, Ludmilla Silva-Pereira, Breno Vilas Boas Raimundo, Gabriel Ferranti Corrêa, Karen Cristina Oliveira, Leandra Naira Zambelli Ramalho, Mèdéton Mahoussi Michaël Boko, Vânia L D Bonato and 2 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Apoptosis : an international journal on programmed cell death, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Death never dies: increasing impact of programmed cell death.Apoptosis : an international journal on programmed cell death · 2025
    Article
  4. Review
  5. In the Eyes of the Beholder-NewInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Ana Carolina Guerta Salina *Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Letícia de Aquino Penteado *Department of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Naiara Naiana DejaniDepartment of Physiology and Pathology, Federal University of Paraíba (UFPB), João Pessoa, Paraíba, Brazil.
Ludmilla Silva-PereiraDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Breno Vilas Boas RaimundoDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Gabriel Ferranti CorrêaDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Karen Cristina OliveiraDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Leandra Naira Zambelli RamalhoDepartment of Pathology and Legal Medicine, Ribeirao Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
Mèdéton Mahoussi Michaël BokoDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
Vânia L D BonatoBasic and Applied Immunology Program, Ribeirao Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
C Henrique SerezaniDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center (VUMC), Nashville, TN, USA.
Alexandra Ivo MedeirosDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil. alexandra.medeiros@unesp.br.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRVanderbilt University Medical Center · USUniversidade Federal da Paraíba · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306363/2013-5Conselho Nacional de Desenvolvimento Científico e Tecnológico 307109/2016-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 471945/2012-9Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 11/17611-7Fundação de Amparo à Pesquisa do Estado de São Paulo 12/23580-0Fundação de Amparo à Pesquisa do Estado de São Paulo 16/10964-5Fundação de Amparo à Pesquisa do Estado de São Paulo 17/04786-0Fundação de Amparo à Pesquisa do Estado de São Paulo 18/19638-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/21629-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/09327-6
6 · The paper itself

Abstract

The removal of dead cells (efferocytosis) contributes to the resolution of the infection and preservation of the tissue. Depending on the environment milieu, macrophages may show inflammatory (M1) or anti-inflammatory (M2) phenotypes. Inflammatory leukocytes are recruited during infection, followed by the accumulation of infected and non-infected apoptotic cells (AC). Efferocytosis of non-infected AC promotes TGF-β, IL-10, and PGE

Indexed as

ApoptosisPhagocytosisAnti-Inflammatory AgentsMacrophagesPhenotypeAnti-Inflammatory AgentsEfferocytosisInfected apoptotic cellsLung inflammationMacrophages

Identifiers

PMID37796354
OpenAlexW4387357940

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.