Evidence map›Paper›PMID 37798539›Full record

ReviewNature reviews. Immunology2024

Cooperation of ILC2s and T

Dietmar M W Zaiss, Edward J Pearce, David Artis, Andrew N J McKenzie, Christoph S N Klose

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. T cell exhaustion in parasitic infections.Frontiers in immunology · 2026
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Dietmar M W ZaissDepartment of Immune Medicine, University Regensburg, Regensburg, Germany. dietmar.zaiss@ukr.de.ORCID http://orcid.org/0000-0003-3596-7062
Edward J PearceBloomberg Kimmel Institute for Cancer Immunotherapy, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David ArtisJill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Andrew N J McKenzieMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID http://orcid.org/0000-0001-9757-2512
Christoph S N KloseDepartment of Microbiology, Infectious Diseases and Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. christoph.klose@charite.de.ORCID http://orcid.org/0000-0001-8803-2979
Bloomberg (United States) · USCornell University · USHumboldt-Universität zu Berlin · DEMRC Laboratory of Molecular Biology · GBUniversity Hospital Regensburg · DE

Funding

Medical Research Council MC_U105178805
6 · The paper itself

Abstract

Type 2 immune responses form a critical defence against enteric worm infections. In recent years, mouse models have revealed shared and unique functions for group 2 innate lymphoid cells and T helper 2 cells in type 2 immune response to intestinal helminths. Both cell types use similar innate effector functions at the site of infection, whereas each population has distinct roles during different stages of infection. In this Perspective, we review the underlying mechanisms used by group 2 innate lymphoid cells and T helper 2 cells to cooperate with each other and suggest an overarching model of the interplay between these cell types over the course of a helminth infection.

Indexed as

HelminthiasisHelminthsParasitesAnimalsCytokinesHumansImmunity, InnateLymphocytesMiceTh2 CellsCytokines

Identifiers

PMID37798539
OpenAlexW4387389384

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.