Evidence map›Paper›PMID 37798944›Full record

ArticleAutophagy2024

Chaperone-mediated autophagy protects against hyperglycemic stress.

Emilio J Vélez, Simon Schnebert, Maxime Goguet, Sara Balbuena-Pecino, Karine Dias, Linda Beauclair, Stéphanie Fontagné-Dicharry, Vincent Véron, Alexandra Depincé, Florian Beaumatin and 2 more

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Emilio J VélezUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0002-6363-0697
Simon SchnebertUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0003-0500-0002
Maxime GoguetUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0009-0006-0615-0175
Sara Balbuena-PecinoUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0001-5101-4814
Karine DiasUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0009-0006-0931-0074
Linda BeauclairUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0002-0124-2664
Stéphanie Fontagné-DicharryUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0002-4366-4590
Vincent VéronUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0003-1469-6443
Alexandra DepincéINRAE, UR1037 Laboratory of Fish Physiology and Genomics, Campus de Beaulieu, Rennes, France.ORCID 0000-0001-7915-3410
Florian BeaumatinUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0001-6017-7172
Amaury HerpinINRAE, UR1037 Laboratory of Fish Physiology and Genomics, Campus de Beaulieu, Rennes, France.ORCID 0000-0002-0630-4027
Iban SeiliezUniversité de Pau et des Pays de l'Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, Saint-Pée-sur-Nivelle, France.ORCID 0000-0002-2202-1756
Université de Pau et des Pays de l'Adour · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chaperone-mediated autophagy (CMA) is a major pathway of lysosomal proteolysis critical for cellular homeostasis and metabolism, and whose defects have been associated with several human pathologies. While CMA has been well described in mammals, functional evidence has only recently been documented in fish, opening up new perspectives to tackle this function under a novel angle. Now we propose to explore CMA functions in the rainbow trout (RT,

Indexed as

Chaperone-Mediated AutophagyGlucoseLysosomesOncorhynchus mykissAnimalsAutophagyHumansHyperglycemiaLysosomal-Associated Membrane Protein 2Molecular ChaperonesReactive Oxygen SpeciesGlucoseLysosomal-Associated Membrane Protein 2Molecular ChaperonesReactive Oxygen SpeciesCMAfishglucose intoleranceLamp2AmetabolismNFE2L2/NRF2

Identifiers

PMID37798944
PMCPMC11062381
OpenAlexW4387393297

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.